中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [138]
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Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Tang, Bi-xi
;
Zhang, Yong
;
Sun, Dan-dan
;
Liu, Qin-yi
;
Li, Cong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/09/26
liver fibrosis
phytochemical
luteolin 7-diglucuronide
HSC activation
PTP1B
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Scalarane sesterterpenes from the South China Sea sponge Hyrtios erecta and their PTP1B inhibitory activity
期刊论文
OAI收割
TETRAHEDRON, 2023, 卷号: 137, 页码: 5
作者:
Sun, Li-Li
;
Shen, Yi-Ran
;
Li, Jia
;
Wang, Jian-Rong
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
Sponge
Hyrtios erecta
Scalarane-type sesterterpene
Configuration
PTP1B
URSOLIC ACID DERIVATIVES BEARING 1,2,3-TRIAZOLE MOIETIES AS POTENTIAL PTP1B INHIBITORS
期刊论文
OAI收割
CHEMISTRY OF NATURAL COMPOUNDS, 2023, 卷号: 59, 期号: 3, 页码: 508-511
作者:
Liu, Zhe
;
Bai, Xueqian
;
Sheng, Li
;
Sun, Liangpeng
;
Li, Jia
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
ursolic acid
PTP1B inhibitors
dose-dependently
molecular docking
Coumaronochromones, flavanones, and isoflavones from the twigs and leaves of Erythrina subumbrans inhibit PTP1B and nitric oxide production
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 206, 页码: 12
作者:
Liu, Cai-Ying
;
Deng, Pan
;
Wang, Bin
;
Liu, Ai-Hong
;
Wang, Meng-Ge
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/04/10
Erythrina subumbrans
Fabaceae
Sesquiterpenoids
Coumaronochromones
Flavanones
Isoflavones
Nitric oxide production inhibition
PTP1B inhibition
Four new phenolic compounds from the fruits of Alpinia galanga
期刊论文
OAI收割
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 75-79
作者:
Liu,Pei
;
Wu,Sheng-Li
;
Wang,Tian
;
Zhang,Xue-Mei
;
Geng,Chang-An
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/07/22
Alpinia galanga
Phenolic compounds
PTP1B inhibitory activity
?-glycosidase inhibitory activity
GLP-1 secretion
Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16148-16159
作者:
Cui,Can
;
Wu,Sheng-Li
;
Chen,Ji-Jun
;
Gongpan,Pianchou
;
Guan,Min
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/07/10
Alpinia oxyphylla
sesquiterpenoids
GLP-1 stimulation
Ca2+/CaMKII and PKA pathways
alpha-glucosidase and PTP1B inhibitory activity
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XXV. Structurally diverse triterpenoids and diterpenoids from two endangered Pinaceae plants endemic to the Chinese Qinling Mountains and their bioactivities
期刊论文
OAI收割
PHYTOCHEMISTRY, 2022, 卷号: 203, 页码: 14
作者:
Jiang, Wei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/09/30
Picea neoveitchii
Larix potaninii var. chinensis
Pinaceae
Endangered plants
Terpenoids
Neoveitchins
Potalarxins
PTP1B
ACC1
Anti-inflammatory and PTP1B inhibitory sesquiterpenoids from the twigs and leaves of Aglaia lawii
期刊论文
OAI收割
FITOTERAPIA, 2022, 卷号: 162, 页码: 7
作者:
Xia, Ming-Jun
;
Zhang, Meng
;
Li, Song-Wei
;
Cai, Zhe-Fei
;
Zhao, Tian-Sheng
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/11/11
Aglaia lawii
Sesquiterpenoids
Amouanglienoids A and B
X-ray diffraction
Anti-inflammatory activity
PTP1B inhibitory activity
Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 16, 页码: 38
作者:
Nurlybekova, Aliya
;
Kudaibergen, Aidana
;
Kazymbetova, Aizhan
;
Amangeldi, Magzhan
;
Baiseitova, Aizhamal
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/09/30
Artemisia genus
TKM
Kazakhstan
sequiterpene lactone
essential oils
flavonoids
alpha-glucosidase
PTP1B
BNA
antioxidant