中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生态环境研究中心 [7]
上海药物研究所 [2]
大连化学物理研究所 [1]
海洋研究所 [1]
烟台海岸带研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [11]
学位论文 [1]
发表日期
2025 [1]
2023 [1]
2020 [1]
2018 [1]
2017 [1]
2016 [1]
更多
学科主题
Chemistry [2]
Pharmacolo... [1]
Toxicology [1]
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共12条,第1-10条
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Drug discovery targeting thyroid hormone receptor f3 (THRf3) for the treatment of liver diseases and other medical indications
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 35-51
作者:
Wang, Kean
;
Chen, Feiyang
;
Wang, Jiang
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Thyroid hormone
Thyroid hormone /3 receptor
MASLD
MASH
THR/3 agonist
Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:
Li, Yuejiao
;
Zhang, Zhenzhong
;
Wang, Jun
;
Shan, Yeqi
;
Tian, Hua
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/07
Thyroid-disrupting chemicals
Thyroid hormone receptor beta
Transthyretin
In vitro screening Assay
Electrochemical biosensor
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos
期刊论文
OAI收割
CHEMOSPHERE, 2017, 卷号: 182, 期号: 0, 页码: 22-30
作者:
Liang, Xuefang
;
Li, Jiajia
;
Martyniuk, Christopher J.
;
Wang, Juan
;
Mao, Yufeng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/07/27
Benzotriazole Ultraviolet Stabilizers
Thyroid Hormone Receptor
Hpt Axis-related Genes
Zebrafish
Toxicological Pathways
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:
Yang, Xianhai
;
Liu, Huihui
;
Liu, Jining
;
Li, Fei
;
Li, Xuehua
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2016/11/30
POLYBROMINATED DIPHENYL ETHERS
THYROID-HORMONE-BINDING
HUMAN SERUM-ALBUMIN
IN-VITRO
ESTROGEN-RECEPTOR
RISK-ASSESSMENT
RECOMBINANT TRANSTHYRETIN
SCIENTIFIC STATEMENT
EVOLUTIONARY CHANGES
CHEMICALS
Structure-activity relations in binding of perfluoroalkyl compounds to human thyroid hormone T3 receptor
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2015, 卷号: 89, 期号: 2, 页码: 233-242
作者:
Ren, Xiao-Min
;
Zhang, Yin-Feng
;
Guo, Liang-Hong
;
Qin, Zhan-Fen
;
Lv, Qi-Yan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2016/03/10
Perfluoroalkyl compounds
Thyroid hormone receptor
Agonistic activity
Gene expression
Molecular docking
Molecular characterization and developmental expression patterns of thyroid hormone receptors (TRs) and their responsiveness to TR agonist and antagonist in Rana nigromaculata
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA, 2014, 卷号: 26, 期号: 10, 页码: 2084-2094
Lou, Qinqin
;
Zhang, Yinfeng
;
Ren, Dongkai
;
Xu, Haiming
;
Zhao, Yaxian
;
Qin, Zhanfen
;
Wei, Wuji
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2015/03/24
Rana nigromaculata
Thyroid hormone receptor
Thyroid hormone signaling
Developmental expression pattern
Responsiveness
Effects of Decabromodiphenyl Ether (BDE-209) on mRNA Transcription of Thyroid Hormone Pathway and Spermatogenesis Associated Genes in Chinese Rare Minnow (Gobiocypris rarus)
期刊论文
OAI收割
ENVIRONMENTAL TOXICOLOGY, 2014, 卷号: 29, 期号: 1, 页码: 1-9
Li, Wei
;
Zhu, Lifei
;
Zha, Jinmiao
;
Wang, Zijian
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2015/03/26
BDE-209
thyroid hormone receptor (TR)
deiodinases
transthyretin
spermatogenesis-associated (spata) gene
rare minnow (Gobiocypris rarus)
Thyroid disruption by technical decabromodiphenyl ether (DE-83R) at low concentrations in Xenopus laevis
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA, 2010, 卷号: 22, 期号: 5, 页码: 744-751
Qin, Xiaofei
;
Xia, Xijuan
;
Yang, Zhongzhi
;
Yan, Shishuai
;
Zhao, Yaxian
;
Wei, Rongguo
;
Li, Yan
;
Tian, Mi
;
Zhao, Xingru
;
Qin, Zhanfen
;
Xu, Xiaobai
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2015/07/31
decabromodiphenyl ether
Xenopus laevis
thyroid disruption
metamorphosis
thyroid hormone receptor