中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生态环境研究中心 [12]
上海药物研究所 [3]
水生生物研究所 [2]
大连化学物理研究所 [1]
高能物理研究所 [1]
海洋研究所 [1]
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OAI收割 [21]
内容类型
期刊论文 [20]
学位论文 [1]
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2025 [1]
2023 [1]
2020 [3]
2018 [1]
2017 [2]
2016 [3]
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学科主题
Chemistry [2]
Pharmacolo... [2]
Environmen... [1]
Oncology [1]
Toxicology [1]
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Drug discovery targeting thyroid hormone receptor f3 (THRf3) for the treatment of liver diseases and other medical indications
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 35-51
作者:
Wang, Kean
;
Chen, Feiyang
;
Wang, Jiang
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Thyroid hormone
Thyroid hormone /3 receptor
MASLD
MASH
THR/3 agonist
Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:
Li, Yuejiao
;
Zhang, Zhenzhong
;
Wang, Jun
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/07
Thyroid-disrupting chemicals
Thyroid hormone receptor beta
Transthyretin
In vitro screening Assay
Electrochemical biosensor
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay
Evaluation and mechanistic study of chlordecone-induced thyroid disruption: Based on in vivo, in vitro and in silico assays
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 716, 页码: 9
作者:
Yang, Lihua
;
Zha, Jinmiao
;
Guo, Yongyong
;
Zhou, Bingsheng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/05/28
Chlordecone
Thyroid disruption
Rare minnow
GH3 cells
Estrogen receptor
Evaluation and mechanistic study of chlordecone-induced thyroid disruption: Based on in vivo, in vitro and in silico assays
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 716, 页码: 1-10
作者:
Yang, Lihua
;
Zha, Jinmiao
;
Guo, Yongyong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/15
Chlordecone
Thyroid disruption
Rare minnow
GH3 cells
Estrogen receptor
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
Structure-Based Investigation on the Binding and Activation of Typical Pesticides With Thyroid Receptor
期刊论文
OAI收割
TOXICOLOGICAL SCIENCES, 2017, 卷号: 160, 期号: 2, 页码: 205-216
作者:
Xiang, Dandan
;
Han, Jian
;
Yao, Tingting
;
Wang, Qiangwei
;
Zhou, Bingsheng
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/07/03
pesticides
thyroid receptor
ligand binding assay
surface plasmon resonance
molecular docking
Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos
期刊论文
OAI收割
CHEMOSPHERE, 2017, 卷号: 182, 期号: 0, 页码: 22-30
作者:
Liang, Xuefang
;
Li, Jiajia
;
Martyniuk, Christopher J.
;
Wang, Juan
;
Mao, Yufeng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/07/27
Benzotriazole Ultraviolet Stabilizers
Thyroid Hormone Receptor
Hpt Axis-related Genes
Zebrafish
Toxicological Pathways
Evaluation and characterization of thyroid-disrupting activities in soil samples along the Second Songhua River, China
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2016, 卷号: 133, 期号: 0, 页码: 475-480
作者:
Kong, Dongdong
;
Wang, Yafei
;
Wang, Jinsheng
;
Teng, Yanguo
;
Li, Na
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2017/03/29
In vitro bioassay
Thyroid receptor
Soil sample
Thyroid-disrupting chemicals
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:
Yang, Xianhai
;
Liu, Huihui
;
Liu, Jining
;
Li, Fei
;
Li, Xuehua
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2016/11/30
POLYBROMINATED DIPHENYL ETHERS
THYROID-HORMONE-BINDING
HUMAN SERUM-ALBUMIN
IN-VITRO
ESTROGEN-RECEPTOR
RISK-ASSESSMENT
RECOMBINANT TRANSTHYRETIN
SCIENTIFIC STATEMENT
EVOLUTIONARY CHANGES
CHEMICALS