中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [52]
海洋研究所 [6]
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中国科学院大学 [3]
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期刊论文 [82]
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Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
期刊论文
OAI收割
BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13
作者:
Zhou, Jianxing
;
Zheng, You
;
Xu, Baohua
;
Long, Songjun
;
Zhu, Li-e
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/03/25
GLP-1RAs
Suicidal or self-injurious behaviors
Pharmacovigilance
FAERS database
Type 2 diabetes
Obesity
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
;
Shen, Shi-yi
;
Duan, Jia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Dimeric styrylpyrones with stimulating GLP-1 secretion activities from Alpinia kwangsiensis
期刊论文
OAI收割
TETRAHEDRON, 2022, 卷号: 120, 页码: 7
作者:
Wu, Meng-Zhen
;
GongPan, Pian-Chou
;
Dai, Meng -Yuan
;
Sun, Peng
;
Xiao, Chun-Fen
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/12/13
Glucagon-like peptide-1
Type 2 diabetes
Alpinia kwangsiensis
Dimeric styrylpyrones
Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 20, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Qingtong
;
Li, Yang
;
Chen, Li-Nan
;
Zhang, Zi-Chen
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/09/30
glucagon-like peptide-1 receptor
type 2 diabetes mellitus
cryoelectron microscopy
peptidomimetic agonism
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14
作者:
Wu, Xing-De
;
Huang, Suling
;
Shi, Yu
;
Shen, Yu
;
Tu, Wen-Chao
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/08/16
Hepatic gluconeogenesis
Type 2 diabetes
Phanginin A derivatives
SIK1
Structural-activity relationship
Microkinetic study of NO oxidation, standard and fast NH3-SCR on CeWOx at low temperatures
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 156, 页码: -
作者:
Liu, Kuo
;
He, Hong
;
Chu, Biwu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2022/01/04
Per-and polyfluoroalkyl substances
Type 2 diabetes
Fasting plasma glucose
Hemoglobin A1c
Lipid fractions
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:
Wang, Yu-zhe
;
Yang, De-hua
;
Wang, Ming-wei
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
glucagon-like peptide-1 receptor
glucose-dependent insulinotropic peptide receptor
peptide 19
LY3298176
heteromerization
type 2 diabetes
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:
Jiang, Bo
;
Luo, Jiao
;
Guo, Shuju
;
Wang, Lijun
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/11
Type 2 diabetes mellitus
Protein tyrosine phosphatase 1B inhibitors
Thiazolidinedione
Insulin signaling
Anti-diabetic activities
Bitter Melon and Diabetes Mellitus
期刊论文
OAI收割
FOOD REVIEWS INTERNATIONAL, 2021
作者:
Gao,Ya
;
Li,Xian
;
Huang,Yanjie
;
Chen,Jianchao
;
Qiu,Minghua
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/04/02
Bitter melon
diabetes mellitus
crude extracts
phyto-metabolites
hypoglycemic mechanism
MOMORDICA-CHARANTIA L.
11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1
ALPHA-GLUCOSIDASE INHIBITION
INSULIN-RESISTANCE
ANTIDIABETIC ACTIVITIES
GUT MICROBIOTA
STRUCTURAL-CHARACTERIZATION
PHENOLIC-COMPOUNDS
OXIDATIVE STRESS
PROTEIN-KINASE