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	Synthesis and Biological Activities of Dihydrooxazolo[5,4-d]- pyrrolo[1,2-a]pyrimidinones 期刊论文 OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 42, 期号: 2, 页码: 543-556 作者: Zeng, Y (Zeng Yan) [1] , [2]; Nie, LF (Nie Lifei) [1]; Niu, C (Niu Chao) [1]; Mamatjan, A (Mamatjan Aytilla) [1] , [2]; Bozorov, K (Bozorov Khurshed) [1] \| 收藏 \| 浏览/下载：93/0 \| 提交时间：2022/05/17 oxazopyrimidinone synthesis bioisosterism anticancer activity antimicrobial activity structure-activity relationships (SARs)
	Lead compound optimization strategy (6) - improving the plasma stability 期刊论文 OAI收割 Acta Pharmaceutica Sinica, 2018, 卷号: 53, 期号: 2, 页码: 192-201 作者: Wu Xiaowei; Wang Jiang; Liu Hong \| 收藏 \| 浏览/下载：49/0 \| 提交时间：2019/01/08 plasma stability structural modification lead compound bioisosterism
	Synthesis and cytotoxicity evaluation of 4-amino-4-dehydroxylarctigenin derivatives in glucose-starved A549 tumor cells 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 3, 页码: 435-437 作者: Lei, Min; Gan, Xianwen; Zhao, Kun; Yu, Qiang; Hu, Lihong \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2019/01/08 Arctigenin (ATG) Natural product Glucose starvation 4-Amino-4-dehydroxylarctigenin Bioisosterism
	Bioisosteric replacement and its application in drug design 期刊论文 OAI收割 Chinese Journal of Medicinal Chemistry, 2014, 卷号: 24, 期号: 3, 页码: 214-230 作者: Zhang Lei; Liu Hong \| 收藏 \| 浏览/下载：32/0 \| 提交时间：2019/01/08 bioisosteric replacement bioisosterism lead compound drug design structural optimization
	The application of the bioisosterism in lead optimization 期刊论文 OAI收割 Chinese Bulletin of Life Sciences, 2006, 卷号: 18, 期号: 2, 页码: 161-167 作者: Cui Yongmei; Nan Fajun \| 收藏 \| 浏览/下载：29/0 \| 提交时间：2019/01/08 bioisosterism lead compound structure optimization