中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
化学研究所 [2]
大连化学物理研究所 [1]
中国科学院大学 [1]
采集方式
OAI收割 [15]
iSwitch采集 [1]
内容类型
期刊论文 [16]
发表日期
2026 [1]
2025 [1]
2024 [2]
2023 [1]
2021 [1]
2020 [1]
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学科主题
物理化学 [1]
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Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 15
作者:
Xiao, Qitao
;
Wang, Yuxian
;
Shen, Zheyuan
;
Mo, Jun
;
Li, Cong
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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
;
Li, Jia
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Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Wu, Jianbo
;
Zhang, Ying
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Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
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Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034
作者:
Song, Shukai
;
Tang, Haotian
;
Ran, Ting
;
Fang, Feng
;
Tong, Linjiang
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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
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Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:
Yang, Xiuyan
;
Deng, Meng
;
Zhang, Xi
;
Wang, Yi
;
Song, Kun
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Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2544-2548
作者:
Wang, Chengyan
;
Liu, Hongchun
;
Song, Zilan
;
Ji, Yinchun
;
Xing, Li
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Insight into the binding mode and the structural features of the pyrimidine derivatives as human A(2A) adenosine receptor antagonists
期刊论文
OAI收割
biosystems, 2014, 卷号: 115, 期号: 1, 页码: 13-22
作者:
Zhang, Lihui
;
Liu, Tianjun
;
Wang, Xia
;
Wang, Jinan
;
Li, Guohui
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