机构

• 上海药物研究所 [8]
• 西北高原生物研究所 [1]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2023 [3]
• 2022 [2]
• 2021 [1]
• 2020 [1]
• 2017 [1]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共9条，第1-9条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14 作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/01/16 Phosphodiesterase-4 (PDE4)  PDE5  Inhibitor  Drug repurposing  Crystal structure  Structure -guided optimization   MEDIATE-Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions 期刊论文  OAI收割 EXPERT OPINION ON DRUG DISCOVERY, 2023, 页码: 13 作者:  Vistoli, Giulio;  Manelfi, Candida;  Talarico, Carmine;  Fava, Anna;  Warshel, Arieh   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Collaborative computing  virtual screening  docking simulations  drug repurposing  SARS-CoV-2  artificial intelligence   ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   Novel niclosamide-derived adjuvants elevating the efficacy of polymyxin B against MDR Pseudomonas aeruginosa DK2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114318 作者:  Lu, Taotao;  Zheng, Xinyu;  Mao, Fei;  Cao, Qiao;  Cao, Qin   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/03/21 Pseudomonas aeruginosa DK2  Polymyxin B  Niclosamide  Adjuvants  Drug repurposing   Drug repurposing for cancer treatment through global propagation with a greedy algorithm in a multilayer network 期刊论文  OAI收割 CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 1, 页码: 74-+ 作者:  Cheng, Xi;  Zhao, Wensi;  Zhu, Mengdi;  Wang, Bo;  Wang, Xuege   |  收藏  |  浏览/下载：271/0  |  提交时间：2024/03/21 Database  drug repurposing  machine learning  network random walk  proteomics analysis   DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5 作者:  Wang, Yongcui;  Yang, Yingxi;  Chen, Shilong;  Wang, Jiguang   |  收藏  |  浏览/下载：40/0  |  提交时间：2021/11/18 drug repurposing  multi-omics data sources  kernel-based data integration  machine learning  cancer precision medicine   Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo   |  收藏  |  浏览/下载：95/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   A systematic analysis of FDA-approved anticancer drugs 期刊论文  OAI收割 BMC SYSTEMS BIOLOGY, 2017, 卷号: 11, 页码: 27-43 作者:  Sun, Jingchun;  Wei, Qiang;  Zhou, Yubo;  Wang, Jingqi;  Liu, Qi   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Anticancer drugs  Drug-cancer network  Cancer-drug-target network  Drug repurposing   Computational Drug Repositioning for Cancer Therapeutics 期刊论文  OAI收割 CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 8, 页码: 767-775 作者:  Jiao, Mingkun;  Liu, Gang;  Xue, Yu;  Ding, Chunyong   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Anticancer drugs  Cancer therapeutics  Computational drug repositioning  Drug discovery  Drug repositioning  Drug repurposing