机构

• 上海药物研究所 [5]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2022 [1]
• 2020 [2]
• 2012 [1]
• 2011 [1]
• 2010 [1]

学科主题

• Biochemica... [1]
• Chemistry,... [1]

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  Darbalaei, Sanaz;  Chang, Ru-lue;  Zhou, Qing-tong;  Chen, Yan;  Dai, An-tao   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/09/30 glucagon-like peptide-1 receptor  glucagon receptor  dual and triple agonist  cAMP  pERK1/2  unimolecular polypharmacology   Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16 作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen   |  收藏  |  浏览/下载：34/0  |  提交时间：2020/12/21 G protein-coupled receptor  Glucagon-like peptide-1 receptor  Glucagon receptor  Biased agonism  Unimolecular dual agonist   Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325 作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.   |  收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24 glucagon receptor  glucagon-like peptide-1 receptor  dual agonist  cryo-electron microscopy  single particle analysis  structure-function  structural biology  peptide 15 (P15)  metabolic disorder  G protein?coupled receptor (GPCR)  glucagon  GLP-1 receptor   Microfractionation bioactivity-based ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of nuclear factor-kappa B inhibitors and beta(2) adrenergic receptor agonists in an alkaloidal extract of the folk herb Alstonia scholaris 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 卷号: 908, 页码: 98-104 作者:  Hou, Yuanyuan;  Cao, Xuelin;  Wang, Liqiang;  Cheng, Binfeng;  Dong, Linyi   |  收藏  |  浏览/下载：71/0  |  提交时间：2013/01/22 Dual-bioactivity-integrated Fingerprinting  Constituent Identification  Nuclear Factor-kappa b Inhibitor  Beta(2) Adrenergic Receptor Agonist  Ultra Performance Liquid Chromatography/quadrupole Time-of-flight Mass Spectrometry   Classification of 5-HT_(1A) receptor agonists and antagonists using GA-SVM method 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2011, 卷号: 32, 期号: 11, 页码: 1424 作者:  Zhu Xuelian;  Cai Haiyan;  Xu Zhijian;  Wang Yong;  Wang Heyao   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 VIVO PHARMACOLOGICAL EVALUATION  SEROTONIN TRANSPORTER AFFINITY  IN-VITRO  DUAL 5-HT1A  REUPTAKE INHIBITORS  LIGANDS  POTENT  DERIVATIVES  DISCOVERY  ANALOGS  5-HT1A receptor  support vector machine  genetic algorithm  agonist  antagonists   Modulated interaction of mu/delta opioid receptors and the drug discovery and design strategy 期刊论文  OAI收割 Chinese Pharmacological Bulletin, 2010, 卷号: 26, 期号: 1, 页码: 4-8 作者:     |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 mu/delta agonist  mu agonist/delta antagonist  opioid analgesics  drug design  low addiction  dual action