中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
心理研究所 [1]
昆明植物研究所 [1]
自动化研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2023 [12]
学科主题
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发表日期:2023
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An efficient synthesis of the last step key intermediate for telmisartan via Pd-catalyzed carbonylative cyclization
期刊论文
OAI收割
TETRAHEDRON, 2023, 卷号: 148, 页码: 8
作者:
Odilov, Abdullajon
;
Qin, Hongjian
;
Bonku, Emmanuel Mintah
;
Zhu, Fuqiang
;
Yang, Feipu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/19
Telmisartan
Benzimidazole
Pd-catalyzed
Carbonylative/cyclization
Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929
作者:
Shen, Donghang
;
Li, Xin
;
Guo, Shimeng
;
Xie, Xin
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
Huntingdon's disease
G protein-coupled receptor
GPR52
alpha-methylene-gamma-butyrolactones
antagonist
Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958
作者:
Ge, Haixia
;
Ji, Beihong
;
Fang, Jiahui
;
Wang, Jiayang
;
Li, Jing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
function-based ligand design
receptor-ligandbinding profile
CB1/CB2
structure-activityrelationship
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Prelimbic cortex dynorphin/& kappa; opioid receptor system modulates methamphetamine-induced cognitive impairment
期刊论文
OAI收割
ADDICTION BIOLOGY, 2023, 卷号: 28, 期号: 9, 页码: 12
作者:
Cheng, Ying-jie
;
Deng, Ying-zhi
;
Deng, Di
;
Wu, Man-qing
;
Chai, Jing-rui
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
cognitive impairment
dynorphin
methamphetamine
prelimbic cortex
& kappa
opioid receptor
GPR84 regulates pulmonary inflammation by modulating neutrophil functions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1665-1675
作者:
Wang, Si-wei
;
Zhang, Qing
;
Lu, Dan
;
Fang, You-chen
;
Yan, Xiao-ci
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
GPR84
acute lung injury
inflammation
neutrophil
ROS
antagonist
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24
作者:
Li, Xiao
;
Li, Fei
;
Ye, Fei
;
Guo, Haotian
;
Chen, Wentao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K/Akt and E-2/ER beta signaling pathways
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 17
作者:
Lyu, Yan
;
Wei, Xiaojia
;
Yang, Xue
;
Li, Jiayuan
;
Wan, Guohui
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/09
11-ethoxyviburtinal
antagonists
anxiety disorder
estrogen receptor beta
PI3K-Akt signaling pathway
the male and female mice
Unsymmetrical Phosphodiesters as GPR84 Antagonists with High Blood Exposure for the Treatment of Lung Inflammation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 8, 页码: 5820-5838
作者:
Li, Shao-Xian
;
Wang, Si-Wei
;
Chen, Lin-Hai
;
Zhang, Qing
;
Lu, Dan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27