中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [559]
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OAI收割 [559]
内容类型
期刊论文 [551]
会议论文 [8]
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2024 [16]
2023 [35]
2022 [39]
2021 [46]
2020 [27]
2019 [29]
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Cell Biolo... [1]
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专题:上海药物研究所
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Palladium(II)-Catalyzed Tandem γ-C(sp
2
)-H Arylation and Cyclization for the Construction of Natural Product-Like Polycyclic Fused
ortho
-Quinone Scaffolds
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 页码: 6
作者:
Li, Xingjun
;
Chen, Yu
;
Xie, Xiong
;
Li, Jing
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism
期刊论文
OAI收割
LIVER INTERNATIONAL, 2024, 页码: 17
作者:
Hou, Aijun
;
Xu, Xiaoding
;
Zhang, Yu
;
He, Hongxiu
;
Feng, Yihan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Drosha degradation
lipid metabolism
miRNA biogenesis
NAFLD
PRMT5
Comprehensive HRMS Screening and Risk Assessments of Aristolochic Acid Analogues in Asari Radix et Rhizoma and Related Commercial Health Products
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 13, 页码: 7438-7456
作者:
Hu, Yun-shu
;
Zhang, Jian-qing
;
Wei, Wen-long
;
Yang, Huan-ya
;
Sha, Fei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
aristolochic acid analogues(AAAs)
Asari Radix et Rhizoma
identification
quantification
toxicity
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
Inulin-like polysaccharide ABWW may impede CCl
4
induced hepatic stellate cell activation through mediating the FAK/PI3K/AKT signaling pathway
in vitro
&
in vivo
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 326, 页码: 15
作者:
Dai, Xiaolan
;
Du, Zhenyun
;
Jin, Can
;
Tang, Bixi
;
Chen, Xia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/19
Fructan
Hepatic fibrosis
Hepatic stellate cells
FAK/PI3K/AKT
Glutamatergic neurons in ventral pallidum modulate heroin addiction via epithalamic innervation in rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 14
作者:
Chen, Ruo-song
;
Liu, Jing
;
Wang, Yu-jun
;
Ning, Kuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/06
heroin addiction
drug taking and seeking
context-induced relapse
ventral pallidum
lateral habenula
glutamatergic neurons