中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [38]
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上海生物化学与细胞... [10]
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期刊论文 [115]
学位论文 [13]
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Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2023, 页码: 10
作者:
Qi, Yu
;
Wang, Zhongle
;
Zhang, Jingwen
;
Tang, Shuhua
;
Zhu, Haoyun
  |  
收藏
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浏览/下载:6/0
  |  
提交时间:2023/12/13
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 20
作者:
Li, Ni
;
Liu, Qiuli
;
Han, Ying
;
Pei, Siyu
;
Cheng, Bisheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKK? and overcomes gefitinib resistance in non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 8, 页码: 1172-1192
作者:
He, Ting
;
Gao, Yinglei
;
Fang, Yanfen
;
Zhang, Yangming
;
Zhang, Shuwei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
HDAC inhibitor
c-Met
IKK?
NSCLC
gefitinib
Characterization of a small-molecule inhibitor targeting NEMO/IKK beta to suppress colorectal cancer growth
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1, 页码: 13
作者:
Yu, Zhenlong
;
Gao, Jian
;
Zhang, Xiaolei
;
Peng, Yulin
;
Wei, Wenlong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15
Xanthotoxol from Saussurea obvallata Attenuates LPS-Induced RAW 264.7 Cells Inflammatory Responses through NF-kappa B Pathway
期刊论文
OAI收割
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2022, 卷号: 48, 期号: 2, 页码: 300
作者:
Wang, WD
;
Zhang, J
;
Liu, ZG
;
Zhu, YH
;
Mei, LJ
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/02
Anti-Inflammatory Functions of Methanol Extract from Malus baccata (L.) Borkh. Leaves and Shoots by Targeting the NF-κB Pathway
期刊论文
OAI收割
PLANTS-BASEL, 2022, 卷号: 11, 期号: 5
作者:
Song, Chaoran
;
Chen, Hongxi
;
Kim, Soo Ah
;
Lee, Jong Sub
;
Choung, Eui Su
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
Malus baccata (L.) Borkh.
anti-inflammatory
NF-kappa B
Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
OAI收割
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery
期刊论文
OAI收割
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455
作者:
Xiang, Shuang
;
Song, Shukai
;
Tang, Haotian
;
Smaill, Jeff B.
;
Wang, Aiqun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/01
Antibiotic resistance
Computational biology
Databases
In silico tools
Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 181, 页码: 357-368
作者:
Guo, Ciliang
;
Wang, Yeqing
;
Zhang, Shihai
;
Zhang, Xiuqi
;
Du, Zhenyun
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
pinnatifida polysaccharide
Colitis
Gut microbiota
Short chain fatty acids