中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共40条，第1-10条

帮助

条数/页：排序方式：
	Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644 作者: Zhang, Yi; Yang, Hong; Li, Bingbing; Li, Jiayi; Li, Huaxuan \| 收藏 \| 浏览/下载：20/0 \| 提交时间：2023/10/17
	Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10 作者: Min, Wenjian; Hou, Zeng; Zhang, Fang; Xie, Shengnan; Yuan, Kai \| 收藏 \| 浏览/下载：13/0 \| 提交时间：2020/07/01 Histone methylation Lysine methyltransferase SET7 Small-molecule inhibitor Virtual screening
	Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文 OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63 作者: Zhu, Kongkai; Du, Daohai; Yang, Rui; Tao, Hongrui; Zhang, Hua \| 收藏 \| 浏览/下载：18/0 \| 提交时间：2020/07/01 polycomb repressive complex 2 EZH2-EED interaction inhibitor virtual screening molecular dynamics simulation
	Reductive methylation labeling, from quantitative to structural proteomics 期刊论文 OAI收割 TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 卷号: 118, 页码: 771-778 作者: Liu, Zheyi; Zhou, Ye; Liu, Jing; Chen, Jin; Heck, Albert J. R. \| 收藏 \| 浏览/下载：99/0 \| 提交时间：2019/12/02 Reductive methylation Stable isotope dimethyl labeling Mass spectrometry Quantitative proteomics N-termini profiling Structural proteomics Lysine reactivity profiling
	A new chromatographic approach to analyze methylproteome with enhanced lysine methylation identification performance 期刊论文 OAI收割 ANALYTICA CHIMICA ACTA, 2019, 卷号: 1068, 页码: 111-119 作者: Wang, Qi; Liu, Zhen; Wang, Keyun; Wang, Yan; Ye, Mingliang \| 收藏 \| 浏览/下载：263/0 \| 提交时间：2019/06/20 Methylproteome Strong cation exchange Immobilized metal ion affinity chromatography High-pH reversed-phase chromatography Lysine methylation identification
	Prediction of ligand modulation patterns on membrane receptors via lyysine reactivity profiling 期刊论文 OAI收割 CHEMICAL COMMUNICATIONS, 2019, 卷号: 55, 期号: 30, 页码: 4311-4314 作者: Zhou, Ye; Liu, Zheyi; Zhang, Jinbao; Dou, Tongyi; Chen, Jin \| 收藏 \| 浏览/下载：70/0 \| 提交时间：2019/06/25
	SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells Through Mediating the Transcriptional Activation of Key Mesendodermal Genes 期刊论文 OAI收割 STEM CELLS, 2019, 卷号: 37, 期号: 11, 页码: 1401-1415 作者: Bai, Hua-Jun; Zhang, Peng; Liang, He; Yang, Huang-Tian; Ma, Li \| 收藏 \| 浏览/下载：18/0 \| 提交时间：2020/12/09 Human embryonic stem cells SET and MYND domain-containing protein 2 Histone methyltransferase Mesendodermal differentiation Brachyury Eomesodermin Mix paired-like homeobox Goosecoid homeobox
	iAcet-Sumo: Identification of lysine acetylation and sumoylation sites in proteins by multi-class transformation methods 期刊论文 OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2018, 卷号: 100, 页码: 144-151 作者: Yang, Yingxi; Wang, Hui; Ding, Jun; Xu, Yan \| 收藏 \| 浏览/下载：27/0 \| 提交时间：2019/12/10
	Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search 期刊论文 OAI收割 MOLECULES, 2018, 卷号: 23, 期号: 3 作者: Ding, Hong; Lu, Wen Chao; Hu, Jun Chi; Liu, Yu-Chih; Zhang, Chen Hua \| 收藏 \| 浏览/下载：49/0 \| 提交时间：2019/01/08 SET7 inhibitor similarity search ligand-based drug design chemical biology probe