中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [60]
西北高原生物研究所 [12]
水生生物研究所 [5]
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期刊论文 [119]
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Two Terpenoid Derivatives with Different 3/5/6/6/5-Fused Pentacyclic Skeletons from Hedyosmum orientale
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 7
作者:
Fan, Yao-Yue
;
Zheng, Cheng-Yu
;
Zhou, Bin
;
Zimbres, Flavia M. M.
;
Cassera, Maria B. B.
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Natural products
C-25 Terpenoids
Structure elucidation
Biosynthetic pathway hypothesis
Antimalarial activity
Picomolar antimalarial agent from a Chinese medicinal plant
期刊论文
OAI收割
SCIENCE CHINA-CHEMISTRY, 2021, 页码: 5
作者:
Zhou, Bin
;
Zimbres, Flavia M.
;
Butler, Joshua H.
;
Xu, Cheng-Hui
;
Haney, Reagan S.
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/12/01
medicinal plants
dimeric sesquiterpenoids
antimalarial agent
structure-activity relationship
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Full-Length Transcriptome Analysis of Plasmodium falciparum by Single-Molecule Long-Read Sequencing
期刊论文
OAI收割
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 卷号: 11, 页码: 11
作者:
Yang, Mengquan
;
Shang, Xiaomin
;
Zhou, Yiqing
;
Wang, Changhong
;
Wei, Guiying
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
Plasmodium falciparum
small protein
long non-coding RNA
alternative splicing
full-length RNA-seq
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
;
Okokon, Jude
;
Ullah, Imran
;
Horrocks, Paul
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:
Liang, Xiaofei
;
Jiang, Zongru
;
Huang, Zhenghui
;
Li, Feng
;
Chen, Cheng
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/11/26
PI4K kinase
Kinase inhibitor
Malaria
Blood stage
Liver stage
Targeting virulence factors as an antimicrobial approach: Pigment inhibitors
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2020, 卷号: 40, 期号: 1, 页码: 293-338
作者:
Ni, Shuaishuai
;
Li, Baoli
;
Xu, Yixiang
;
Mao, Fei
;
Li, Xiaokang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
antimicrobial
colored pathogens
CrtN inhibitor
staphyloxanthin
virulence factor pigment
Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, 卷号: 35
作者:
Li, Xia
;
Ni, Maowei
;
Xu, Xiaoling
;
Chen, Wei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/11/30
Glutathione reductase
isothiocyanate
inhibitor
thiocarbamoylation
Trends in Molecular Markers Associated with Resistance to Sulfadoxine-Pyrimethamine (SP) Among Plasmodium falciparum Isolates on Bioko Island, Equatorial Guinea: 2011-2017
期刊论文
OAI收割
INFECTION AND DRUG RESISTANCE, 2020, 卷号: 13, 页码: 1203, 1212
作者:
Lin, Li-Yun
;
Li, Jian
;
Huang, Hui-Ying
;
Liang, Xue-Yan
;
Jiang, Ting-Ting
  |  
收藏
  |  
浏览/下载:148/0
  |  
提交时间:2020/09/22
malaria
drug resistance
dihydrofolate reductase
dihydropteroate synthase
sulfadoxine-pyrimethamine