机构

• 上海药物研究所 [69]
• 西北高原生物研究所 [9]
• 上海有机化学研究所 [6]
• 中国科学院大学 [5]
• 过程工程研究所 [4]
• 西双版纳热带植物园 [3]
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采集方式

• OAI收割 [108]
• iSwitch采集 [6]

内容类型

• 期刊论文 [113]
• 会议论文 [1]

发表日期

• 2022 [3]
• 2021 [4]
• 2019 [5]
• 2018 [3]
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• 2016 [8]
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学科主题

• Pharmacolo... [4]
• 生命有机化学 [4]
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• 天然产物有机化学 [2]
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筛选

浏览/检索结果: 共114条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 OTTM: an automated classification tool for translational drug discovery from omics data 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2023, 页码: 12 作者:  Yang, Xiaobo;  Zhang, Bei;  Wang, Siqi;  Lu, Ye;  Chen, Kaixian   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 OTTM  omics data  translational drug discovery  literature mining  hepatocellular carcinoma   Two Terpenoid Derivatives with Different 3/5/6/6/5-Fused Pentacyclic Skeletons from Hedyosmum orientale 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 7 作者:  Fan, Yao-Yue;  Zheng, Cheng-Yu;  Zhou, Bin;  Zimbres, Flavia M. M.;  Cassera, Maria B. B.   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Natural products  C-25 Terpenoids  Structure elucidation  Biosynthetic pathway hypothesis  Antimalarial activity   Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7 作者:  Tong, Xiao;  Chen, Li;  He, Shi-jun;  Zuo, Jian-ping   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/09/30 artemisinin derivative  beta-aminoarteether maleate (SM934)  autoimmune and inflammatory diseases  T helper cells  macrophages  inflammatory cytokines   Cephalotane-Type Norditerpenoids from Cephalotaxus fortunei var. alpina 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 1177-1184 作者:  Ge, Zhan-Peng;  Zhou, Bin;  Zimbres, Flavia M.;  Cassera, Maria B.;  Zhao, Jin-Xin   |  收藏  |  浏览/下载：19/0  |  提交时间：2022/06/15 Cephalotaxus fortunei var  alpine  Natural products  Structural elucidation  Cephalotane norditerpenoids  Antimalarial activity   Picomolar antimalarial agent from a Chinese medicinal plant 期刊论文  OAI收割 SCIENCE CHINA-CHEMISTRY, 2021, 页码: 5 作者:  Zhou, Bin;  Zimbres, Flavia M.;  Butler, Joshua H.;  Xu, Cheng-Hui;  Haney, Reagan S.   |  收藏  |  浏览/下载：66/0  |  提交时间：2021/12/01 medicinal plants  dimeric sesquiterpenoids  antimalarial agent  structure-activity relationship   Screening of alternative solvent ionic liquids for artemisinin: COSMO-RS prediction and experimental verification 期刊论文  OAI收割 JOURNAL OF MOLECULAR LIQUIDS, 2021, 卷号: 338, 页码: 10 作者:  Cao, Yingying;  Wu, Zhixing;  Zhang, Ying;  Liu, Yanrong;  Wang, Hui   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/06/15 Artemisinin  Ionic Liquids  COSMO-RS  Solubility  Hydrogen Bond   Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文  OAI收割 ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893 作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna   |  收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04 OZ439 (artefenomel)  malaria  metabolite identification  cytochrome P450 metabolism  cytochrome P450 inhibition  time-dependent inhibition   In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues 期刊论文  OAI收割 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11 作者:  Uche, Fidelia Ijeoma;  Guo, Xiaozhen;  Okokon, Jude;  Ullah, Imran;  Horrocks, Paul   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 malaria  Plasmodium falciparum  Plasmodium berghei  bisbenzylisoquinoline alkaloids  cycleanine  metabolism  in vivo activity  antimalarial agents  drug metabolism   Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds 期刊论文  OAI收割 FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12 作者:  Liu, Congshan;  Yin, Jianhai;  Yao, Jiaqing;  Xu, Zhijian;  Tao, Yi   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 echinococcosis  Echinococcus multilocularis  pharmacophore modeling  virtual screenings  in vitro drug screen  cytotoxicity  E  multilocularis-infected mice  pharmacokinetics analysis   Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188 作者:  Liang, Xiaofei;  Jiang, Zongru;  Huang, Zhenghui;  Li, Feng;  Chen, Cheng   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/11/26 PI4K kinase  Kinase inhibitor  Malaria  Blood stage  Liver stage