中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [105]
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期刊论文 [423]
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PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 1, 页码: 129-140
作者:
He, Weizhi
;
Yin, Xiaotong
;
Xu, Chu
;
Liu, Xiangyue
;
Huang, Yue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
Chemical Inhibitors Targeting the Oncogenic m
6
A Modifying Proteins
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022
作者:
Huang, Yue
;
Xia, Wenyang
;
Dong, Ze
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
Genome-wide epigenetic dynamics during postnatal skeletal muscle growth in Hu sheep
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2023, 卷号: 6, 期号: 1, 页码: 20
作者:
Cao, Yutao
;
Ai, Yue
;
Zhang, Xiaosheng
;
Zhang, Jinlong
;
Long, Xianlei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/21
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter
期刊论文
OAI收割
BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20
作者:
Ren, Ganglin
;
Li, Hongyan
;
Hong, Dan
;
Hu, Fangyu
;
Jin, Rongjia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
LINC00955
Colorectal cancer
Cell cycle
CDK2
PHIP
Sp1
Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 22
作者:
Xiao, Pan
;
Duan, Zongliang
;
Liu, Zeyu
;
Chen, Liang
;
Zhang, Deyan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19
作者:
Cao, Yinghao
;
Lin, Yexuan
;
Sun, Na
;
Du, Xinyi
;
Dong, Yixin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
small RNA
herbal decoction
cross-kingdom regulation
traditional Chinese medicine
RNA oligonucleotide drug
RNA therapeutics
Bencao small RNA Atlas
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
A patent review of PRMT5 inhibitors to treat cancer (2018-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28
作者:
Gao, Jing
;
Yang, Jie
;
Xue, Shengyu
;
Ding, Hong
;
Lin, Hua
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
PRMT5
inhibitor
epigenetic target
cancer treatment
combined treatment