中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2022 [1]
2021 [1]
2020 [2]
2019 [1]
2018 [2]
2017 [2]
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Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 870-881
作者:
Pang, Xiaoyan
;
Tang, Chongzhuang
;
Cao, Peng
;
Zhou, Lei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Retrorsine
bile acid
oxidative stress
reactive metabolite
transporter
Nrf2
Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
JOURNAL OF FOOD AND DRUG ANALYSIS, 2018, 卷号: 26, 期号: 3, 页码: 965-972
作者:
Ma, Jiang
;
Xia, Qingsu
;
Fu, Peter P.
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloids
Pyrrole-protein adducts
Covalent binding
Target protein
Mechanism-based biomarker
Clinical diagnosis
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids
期刊论文
OAI收割
Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews, 2017, 卷号: 35, 期号: 3, 页码: 127-139
作者:
Li, Na
;
Zhang, Fan
;
Lian, Wei
;
Wang, Huali
;
Zheng, Jiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
Chemico-biological interactions, 2016, 卷号: 243, 页码: 119-26
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Fu, Peter P
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08