机构

• 上海药物研究所 [450]

采集方式

• OAI收割 [450]

内容类型

• 期刊论文 [343]
• 项目 [97]
• 会议论文 [7]
• 学位论文 [2]
• 专著章节 [1]

发表日期

• 2024 [5]
• 2023 [21]
• 2022 [24]
• 2021 [32]
• 2020 [19]
• 2019 [20]
• 更多

学科主题

• Chemistry [3]
• Life Scien... [2]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共450条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Formyl phloroglucinol meroterpenoids from the leaves of Eucalyptus globulus subsp. maidenii and their ATP-citrate lyase inhibitory activities 期刊论文  OAI收割 FITOTERAPIA, 2024, 卷号: 173, 页码: 6 作者:  Hu, Zhu;  Liu, Yi-Nan;  Yu, Mei-Hua;  Hou, Ai -Jun;  Li, Jing-Ya   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/13 Eucalyptus globulus subsp. maidenii  Meroterpenoids  ATP-citrate lyase   Meta-MolNet: A Cross-Domain Benchmark for Few Examples Drug Discovery 期刊论文  OAI收割 IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 15 作者:  Lv, Qiujie;  Chen, Guanxing;  Yang, Ziduo;  Zhong, Weihe;  Chen, Calvin Yu-Chian   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 Benchmark platform  cross-domain meta-learning  drug discovery  few examples  Meta-MolNet  molecular property   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13 作者:  Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/02/27 HPK1 inhibitor  machine learning  virtual screening  free energy perturbation  structural modification   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Sterically demanding Csp2(ortho-substitution)-Csp3(tertiary) bond formation via carboxylate-directed Mizoroki-Heck reaction under extra-ligand-free conditions 期刊论文  OAI收割 ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 页码: 5 作者:  Zeng, Wei;  Chen, Ai-Wen;  Yan, Ming-Jie;  Wang, Jie   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/01/16 Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221 作者:  Xie, Chenghu;  Liu, Bo;  Song, Zilan;  Yang, Ye;  Dai, Mengdi   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/02/27 High-throughput design of energetic molecules 期刊论文  OAI收割 JOURNAL OF MATERIALS CHEMISTRY A, 2023, 卷号: 11, 期号: 45, 页码: 25031-25044 作者:  Liu, Jian;  Zhao, Shicao;  Duan, Bowen;  He, Xudong;  Yang, Chunming   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Unprecedented sesterterpenoids, orientanoids A-C: discovery, bioinspired total synthesis and antitumor immunity 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 页码: 9 作者:  Zheng, Cheng-Yu;  Zhao, Jin-Xin;  Yuan, Chang-Hao;  Peng, Xia;  Geng, Meiyu   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19