中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [67]
采集方式
OAI收割 [67]
内容类型
期刊论文 [67]
发表日期
2023 [7]
2022 [3]
2021 [3]
2020 [6]
2019 [9]
2018 [5]
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专题:上海药物研究所
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
The in vivo drug delivery pattern of the organelle-targeting small molecules
期刊论文
OAI收割
ADVANCED DRUG DELIVERY REVIEWS, 2023, 卷号: 200, 页码: 14
作者:
Fang, Zhao
;
Chen, Hao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Organelle-targeting
In vivo imaging
Small molecular probe
Biodistribution
Subcellular structure
Human disease
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Superoxide anion monitoring in epileptic brains with a near-infrared fluorescent probe
期刊论文
OAI收割
DYES AND PIGMENTS, 2023, 卷号: 213, 页码: 111155
作者:
Ying, Weiwu
;
Dong, Fuxing
;
Shi, Yifan
;
Zhan, Ziyi
;
Wang, Shuwan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Fluorescent probe
Near -infrared
Superoxide anions
Epilepsy
Living Cells and Cell-Derived Vesicles: A Trojan Horse Technique for Brain Delivery
期刊论文
OAI收割
PHARMACEUTICS, 2023, 卷号: 15, 期号: 4, 页码: 1257
作者:
Ou, Ante
;
Wang, Yuewei
;
Zhang, Jiaxin
;
Huang, Yongzhuo
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
brain drug delivery
blood-brain barrier (BBB)
Trojan horse delivery systems
cells
extracellular vesicles
cell membranes
Fluorescent "AND " logic gates for simultaneous detection of thiols and protons: photophysical properties, mechanism and bioimaging of living cells
期刊论文
OAI收割
ANALYTICAL METHODS, 2023, 卷号: 15, 期号: 6, 页码: 818-828
作者:
Zhou, Langping
;
Yu, Zhihao
;
Zhang, Guangzhu
;
Jin, Zechen
;
Zhang, Weibing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Generation of an Aptamer Targeting Receptor-Type Tyrosine-Protein Phosphatase F
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2023, 页码: 6
作者:
Lv, Jing
;
Zhen, Xiaoxiao
;
Li, Dandan
;
Liao, Guomiao
;
Long, Zhenhao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Making Protein Degradation Visible: Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 13
作者:
Cheng, Junfei
;
He, Shipeng
;
Xu, Jun
;
Huang, Min
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/04/10
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:
Sun, Haiguo
;
Xi, Mengyu
;
Jin, Qiang
;
Zhu, Zhengdan
;
Zhang, Yani
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/09/30
Fluorescent probes for the detection of disease-associated biomarkers
期刊论文
OAI收割
SCIENCE BULLETIN, 2022, 卷号: 67, 期号: 8, 页码: 853-878
作者:
Dou, Wei-Tao
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Zhu, Guo-Biao
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/16
Fluorescent probes
Fluorescence imaging
Biomarker detection
Chemical biology