机构

• 上海药物研究所 [29]

采集方式

• OAI收割 [29]

内容类型

• 期刊论文 [29]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [2]
• 2020 [1]
• 2019 [4]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共29条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Late-Stage Functionalization for the Divergent Synthesis of Podophyllotoxin Derivatives by Rhodium Catalysis 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 10 作者:  Zhao, Yue;  Shen, Yangpeng;  He, Jian;  Li, Jing;  Zhou, Shengbin   |  收藏  |  浏览/下载：138/0  |  提交时间：2023/10/17 anticancer  C-H bond activation  divergent synthesis  podophyllotoxin  late-stage functionalization   Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 88, 期号: 6, 页码: 3808-3821 作者:  Zhu, Huajian;  Wang, Jiang;  Lu, Yunfu;  Soloshonok, Vadim A.;  Lan, Lefu   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Cyclic enhancement of hypoxic microenvironment via an intelligent nanoamplifier for activated NIR-II fluorescence/photoacoustic imaging-guided precise synergistic therapy 期刊论文  OAI收割 MATERIALS TODAY BIO, 2022, 卷号: 17, 页码: 10 作者:  Zheng, Ziliang;  Chen, Xuejiao;  Dai, Rong;  Wu, Shutong;  Kang, Weiwei   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Second near -infrared window  Dual -modal imaging  Activatable NIR-II FL Imaging  Tumor hypoxia  Synergistic tumor therapy   Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2022, 页码: 4 作者:  Li, Jian;  Sun, Jina;  Zhang, Xianglei;  Zhang, Ruxue;  Wang, Qian   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10 pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate 期刊论文  OAI收割 JOURNAL OF PROTEOMICS, 2020, 卷号: 210, 页码: 11 作者:  Jia, Xinglong;  Pan, Lulu;  Zhu, Mingrui;  Hu, Hao;  Zhai, Linhui   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 E7070  pSILAC  LysC-Trypsin  LysN-LysArgiNase  PRPF39  DCAF15  Degradation   Dynamic modifications of biomacromolecules: mechanism and chemical interventions 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1459-1471 作者:  Wang, Chu;  Zou, Peng;  Yang, Caiguang;  Liu, Lei;  Cheng, Liang   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 chemical biology  biomacromolecule  dynamic modification  modification analysis  chemical intervention   Highly selective C-H bond activation of N-arylbenzimidamide and divergent couplings with diazophosphonate compounds: a catalyst-controlled selective synthetic strategy for 3-phosphorylindoles and 4-phosphorylisoquinolines 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 3, 页码: 393-398 作者:  Yang, Qiaolan;  Wu, Chenglin;  Zhou, Jianhui;  He, Guoxue;  Liu, Hong   |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 dynamicmodificationsofbiomacromoleculesmechanismandchemicalinterventions 期刊论文  OAI收割 sciencechinalifesciences, 2019, 卷号: 62, 期号: 11, 页码: 1459 作者:  Wang Chu;  Zou Peng;  Yang Caiguang;  Liu Lei;  Cheng Liang   |  收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 POSTTRANSLATIONAL MODIFICATIONS  PROTEIN LIPIDATION  DNA METHYLATION  TARGET  IDENTIFICATION  GLYCOSYLATION  CHEMISTRY  HEALTH  DYRK2  P53  chemical biology  biomacromolecule  dynamic modification  modification analysis  chemical intervention