中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [85]
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OAI收割 [85]
内容类型
期刊论文 [83]
会议论文 [1]
学位论文 [1]
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2023 [5]
2022 [5]
2021 [2]
2020 [9]
2019 [2]
2018 [8]
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Pharmacolo... [1]
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专题:上海药物研究所
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The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
A zinc-modified
Anemarrhena asphodeloides
polysaccharide complex enhances immune activity
via
the NF-?B and MAPK signaling pathways
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 249, 页码: 12
作者:
Zhang, Shaojie
;
Zhang, Qian
;
Li, Chong
;
Xing, Na
;
Zhou, Pengfei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Anemarrhena asphodeloides Bunge
Zinc modification
Immunoregulatory activity
Zebrafish
NF-kappa B signaling pathway
MAPKs signaling pathway
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
“Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis
期刊论文
OAI收割
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Jiaxin
;
Ou,Ante
;
Tang,Xueping
;
Wang,Rong
;
Fan,Yujuan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/09/09
Ulcerative colitis
Colonic drug delivery
Patchouli alcohol
Simvastatin
Inflammatory microenvironment
Anti-fibrosis
The orphan G protein-coupled receptor GPR149 is a negative regulator of myelination and remyelination
期刊论文
OAI收割
GLIA, 2022, 页码: 17
作者:
Suo, Na
;
He, Bingqing
;
Cui, Shihao
;
Yang, Ying
;
Wang, Min
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/08/16
GPR149
MAPK
ERK pathway
myelination
oligodendrocyte
oligodendrocyte progenitor cell
remyelination
Spermine alleviates experimental autoimmune encephalomyelitis via regulating T cell activation and differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 卷号: 107, 页码: 11
作者:
Zheng, Ruting
;
Kong, Miaomiao
;
Wang, Siwei
;
He, Bingqing
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Spermine
Polyamines
Multiple Sclerosis
EAE
Th1
Th17
MAPK pathway
ERK