机构

• 上海药物研究所 [56]

采集方式

• OAI收割 [56]

内容类型

• 期刊论文 [56]

发表日期

• 2024 [1]
• 2023 [4]
• 2022 [9]
• 2021 [5]
• 2020 [2]
• 2019 [2]
• 更多

学科主题

• Cell Biolo... [1]
• Physiology [1]

筛选

浏览/检索结果: 共56条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway 期刊论文  OAI收割 Food Science and Human Wellness, 2023 作者:  Li, Lan;  Yang, Shengye;  Liang, Xinyu;  Liu, Yameng;  Xu, Hualing   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/26 Gut Microbiota  Non-alcoholic Fatty Liver Disease  Ssd  Bile Acids  Farnesoid x Receptor   Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis 期刊论文  OAI收割 CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+ 作者:  Kuang, Junliang;  Wang, Jieyi;  Li, Yitao;  Li, Mengci;  Zhao, Mingliang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Zhong, Jing;  He, Xiaofang;  Gao, Xinxin;  Liu, Qiaohong;  Zhao, Yu   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08 Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter 期刊论文  OAI收割 PHYTOTHERAPY RESEARCH, 2023, 页码: 15 作者:  Wang, YuKun;  Li, Jing;  Wu, Li;  Qin, XueMei;  Xie, Cen   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 bile acids  enterohepatic circulation  FXR-related genes  saikosaponins   Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities 期刊论文  OAI收割 PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22 作者:  Xie, Ningjie;  Wang, Hong;  Qin, Hua;  Guo, Zitao;  Xue, Hao   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 hepatic impairment  ezetimibe  active metabolites  phase II enzymes  transporters  first-pass metabolism  inhibitory bile acids   Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16 作者:  Yan, Ying;  Niu, Zhoumin;  Sun, Chao;  Li, Peng;  Shen, Siyi   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/13 Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/11/11 Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal 期刊论文  OAI收割 CELL STEM CELL, 2022, 卷号: 29, 期号: 9, 页码: 1366-+ 作者:  Chen, Li;  Jiao, Tingying;  Liu, Weiwei;  Luo, Yuhong;  Wang, Jue   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者:  Sun, Renqiang;  Zhang, Zhiyong;  Bao, Ruoxuan;  Guo, Xiaozhen;  Gu, Yuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 SIRT5  bile acid  macrophage polarization  immunosuppressive tumor microenvironment  liver cancer