中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [31]
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Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:  
Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan
  |  收藏  |  浏览/下载:7/0  |  提交时间:2023/12/19
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:  
Kong, Linghui;  Shu, Xuelian;  Tang, Siyuan
  |  收藏  |  浏览/下载:42/0  |  提交时间:2022/08/30
Concise synthesis of N-phosphorylated amides through three-component reactions 期刊论文  OAI收割
GREEN CHEMISTRY, 2021, 页码: 5
作者:  
Zhu, Yuan-Yuan;  Zhang, Tao;  Zhou, Linlin;  Yang, Shang-Dong
  |  收藏  |  浏览/下载:17/0  |  提交时间:2021/12/16
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  
He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
  |  收藏  |  浏览/下载:83/0  |  提交时间:2021/11/04
Diterpene Biosynthesis in Catenulispora acidiphila: On the Mechanism of Catenul-14-en-6-ol Synthase 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:  
Li, Geng;  Guo, Yue-Wei;  Dickschat, Jeroen S.
  |  收藏  |  浏览/下载:84/0  |  提交时间:2021/05/24
Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:  
Shi, Wei;  Tang, Feng;  Ao, Jiwei;  Yu, Qun;  Liu, Junjie
  |  收藏  |  浏览/下载:129/0  |  提交时间:2020/12/21
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9
作者:  
Wu, Qihao;  Li, Song-Wei;  Xu, Heng;  Wang, Hong;  Hu, Pei
  |  收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  
Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
  |  收藏  |  浏览/下载:80/0  |  提交时间:2020/07/01
Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal 期刊论文  OAI收割
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 372, 页码: 8
作者:  
Guo, Liu-bin;  Yu, Chuan;  Ling, Qing-lan;  Fu, Yu;  Wang, Yu-jun
  |  收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:  
Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao
  |  收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33