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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [31]
采集方式
OAI收割 [31]
内容类型
期刊论文 [31]
发表日期
2023 [1]
2022 [1]
2021 [2]
2020 [3]
2019 [4]
2018 [1]
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Neuroscien... [1]
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专题:上海药物研究所
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Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/08/30
Concise synthesis of N-phosphorylated amides through three-component reactions
期刊论文
OAI收割
GREEN CHEMISTRY, 2021, 页码: 5
作者:
Zhu, Yuan-Yuan
;
Zhang, Tao
;
Zhou, Linlin
;
Yang, Shang-Dong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/12/16
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
Diterpene Biosynthesis in Catenulispora acidiphila: On the Mechanism of Catenul-14-en-6-ol Synthase
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Li, Geng
;
Guo, Yue-Wei
;
Dickschat, Jeroen S.
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/05/24
biosynthesis
enzyme mechanisms
isotopes
substrate analogues
terpenoids
Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Shi, Wei
;
Tang, Feng
;
Ao, Jiwei
;
Yu, Qun
;
Liu, Junjie
  |  
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2020/12/21
acylation
click chemistry
peptides
rearrangements
silver
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9
作者:
Wu, Qihao
;
Li, Song-Wei
;
Xu, Heng
;
Wang, Hong
;
Hu, Pei
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
biomimetic synthesis
biosynthetic rearrangements
marine natural products
polyketides
Sacoglossan mollusk
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal
期刊论文
OAI收割
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 372, 页码: 8
作者:
Guo, Liu-bin
;
Yu, Chuan
;
Ling, Qing-lan
;
Fu, Yu
;
Wang, Yu-jun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Morphine withdrawal
Aversive memories
Proteomics
Synaptic plasticity
Amygdala
Dorsal hippocampus
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:
Wang, Yuxiang
;
Li, Xian
;
Liu, Xueling
;
Chen, Yi
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
PI3K alpha
CDK4/6
KRAS
NSCLC
CYH33