中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [293]
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OAI收割 [293]
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期刊论文 [287]
会议论文 [6]
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2024 [4]
2023 [25]
2022 [27]
2021 [35]
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2019 [33]
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共293条,第1-10条
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专题:上海药物研究所
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A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
;
Zhang, Mengge
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
A Near-infrared Fluorescence and Positron Emission Tomography Bimodal Probe for
I
n Vivo
I
maging of Amyloid-β Species
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 3, 页码: 472-478
作者:
Fang, Daqing
;
Pan, Donghui
;
Wen, Xidan
;
Zhang, Junya
;
Yang, Min
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/13
A beta species
Alzheimer's disease
NIR fluorescence imaging
PET imaging
bimodalprobe
APP/PS1
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14
作者:
Chen, Xi
;
Yang, Jia-bin
;
Cao, Hui-hui
;
Fang, Xiao-chuan
;
Liu, Shan-hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Liang-Ge-San
Dengue virus serotype 2
Heat shock protein 70
Caveolin1
Envelope protein
Densely Functionalized Macrocyclic Sesquiterpene Pyridine Alkaloids from
Maytenus austroyunnanensis
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2023, 页码: 11
作者:
Ji, Kai-Long
;
Fan, Yao-Yue
;
Gong, Qi
;
Liu, Qun-Fang
;
Cui, Ming-Jun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment