中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [92]
采集方式
OAI收割 [92]
内容类型
期刊论文 [85]
会议论文 [7]
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2024 [1]
2023 [4]
2022 [10]
2021 [2]
2020 [8]
2019 [8]
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学科主题
Chemistry [2]
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浏览/检索结果:
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专题:上海药物研究所
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Cui, Shi-hao
;
Suo, Na
;
Yang, Ying
;
Wu, Xuan
;
Guo, Shi-meng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
remyelination
U73122
A pilot study of the differentiated landscape of peripheral blood mononuclear cells from children with incomplete versus complete Kawasaki disease
期刊论文
OAI收割
WORLD JOURNAL OF PEDIATRICS, 2023, 页码: 12
作者:
Sun, Shu-Na
;
Zhou, Yan
;
Fu, Xing
;
Zheng, Yuan-Zheng
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388
作者:
  |  
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2023/10/17
A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19
作者:
Cao, Yinghao
;
Lin, Yexuan
;
Sun, Na
;
Du, Xinyi
;
Dong, Yixin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
small RNA
herbal decoction
cross-kingdom regulation
traditional Chinese medicine
RNA oligonucleotide drug
RNA therapeutics
Bencao small RNA Atlas
Discovery of Novel N-(5-(Pyridin-3-yl)-1H-indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 19
作者:
Yang, Bowen
;
Zhang, Haoran
;
Li, Na
;
Gao, Lixin
;
Jiang, Hong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Determination of six core components from Mahuang Xuanfei Zhike syrup in rat plasma and tissues by UPLC-MS/MS: Application to a pharmacokinetics and tissue distribution study
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 15
作者:
Yang, Yang
;
Zhu, Jing
;
Yao, Chang-liang
;
Guo, De-an
;
He, Na
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/11
Mahuang Xuanfei Zhike syrup
pharmacokinetics
tissue distribution
UPLC-MS
MS
SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Guo, Qian-bei
;
Zhan, Li
;
Xu, Hai-yan
;
Gao, Zhao-bing
;
Zheng, Yue-ming
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/30
early infantile epileptic encephalopathy type 13
SCN8A
gain-of-function mutation
antiepileptic drugs
phenytoin
carbamazepine
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia
期刊论文
OAI收割
FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 卷号: 9, 页码: 13
作者:
Liu, Nan
;
Guo, Yu-Na
;
Wang, Xiao-Jin
;
Ma, Jue
;
He, Yun-Ting
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/16
preeclampsia
APOBEC3A
lipid metabolism
copy number variation
genetics
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15