中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [52]
采集方式
OAI收割 [52]
内容类型
期刊论文 [50]
会议论文 [2]
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2023 [6]
2022 [5]
2021 [5]
2020 [3]
2018 [6]
2017 [2]
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专题:上海药物研究所
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Development of HSP90 inhibitors-SN38 conjugates for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11
作者:
Cao, Yuting
;
Shen, Qianqian
;
Ding, Mengyuan
;
Chen, Yi
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2023/10/17
HSP90
SN38 conjugate
Drug accumulation
Cancer treatment
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:
Cao, Bi-rong
;
Huang, Yi-ming
;
Tian, Fu-yun
;
Li, Jin-hui
;
Xu, Chun-long
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 34, 页码: 5051-5054
作者:
Wu, Yueci
;
Han, Hai-Hao
;
He, Liu
;
Li, Li
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Recent advances in developing active targeting and multifunctional drug delivery systems via bioorthogonal chemistry
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Yi Wenzhe
;
Xiao Ping
;
Liu Xiaochen
;
Zhao Zitong
;
Sun Xiangshi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/05/22
Recent advances in developing active targeting and multi-functional drug delivery systems via bioorthogonal chemistry
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1, 页码: 25
作者:
Yi, Wenzhe
;
Xiao, Ping
;
Liu, Xiaochen
;
Zhao, Zitong
;
Sun, Xiangshi
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/04/10
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:
Qian, Hong-jie
;
Wang, Yu
;
Zhang, Meng-qi
;
Xie, Yuan-chao
;
Wu, Qing-qing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
VV116
nucleoside analog
SARS-CoV-2
safety
pharmacokinetics
healthy subjects
Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody
期刊论文
OAI收割
SCIENCE, 2022, 卷号: 375, 期号: 6584, 页码: 1048-+
作者:
Yin, Wanchao
;
Xu, Youwei
;
Xu, Peiyu
;
Cao, Xiaodan
;
Wu, Canrong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15