中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [584]
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OAI收割 [584]
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期刊论文 [575]
会议论文 [9]
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2024 [7]
2023 [33]
2022 [39]
2021 [44]
2020 [27]
2019 [40]
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Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells (vol 41, pg 270, 2020)
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 2
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/06
Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6
作者:
Fan, Shu-Hui
;
Chang, Yuan
;
Xiong, Xiao-Yu
;
Xiang, Mai
;
Yuan, Wen-Long
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
DZ2002
Osteoarthritis
Osteoclast
Bone resorption
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
Lin, Jia-Ling
;
Chen, Longxian
;
Wu, Wen-Kai
;
Guo, Xiao-Xiang
;
Yu, Cheng-Hui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably