中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
采集方式
OAI收割 [24]
内容类型
期刊论文 [23]
会议论文 [1]
发表日期
2024 [1]
2023 [4]
2022 [3]
2021 [2]
2019 [1]
2018 [2]
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浏览/检索结果:
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专题:上海药物研究所
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Five undescribed abietane-type diterpenes of Callicarpa macrophylla
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 170, 页码: 10
作者:
Du, Gao-Xiang
;
Chen, Tong
;
Wang, Ge
;
Liu, Ying-Bo
;
Zheng, Liu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Callicarpa macrophylla
Verbenaceae
Abietane-type diterpenoids
PCSK9
Macrophypene F -J
The heparan sulfate mimetic Muparfostat aggravates steatohepatitis in obese mice due to its binding affinity to lipoprotein lipase
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 卷号: 180, 期号: 14, 页码: 1803-1818
作者:
Zhang, Jia
;
Li, Kai
;
Sun, Hao-Ran
;
Sun, Shao-Kun
;
Zhu, Ya-Ting
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
heparan sulfate mimetic
heparanase inhibitor
hepatic steatosis
lipoprotein lipase
obesity
Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201
作者:
Cheng, Yaxin
;
Tao, Jinsong
;
Zhang, Yaqi
;
Xi, Long
;
Han, Run
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
mesoporous silica nanoparticles (MSNs)
toxicity
shape
shear stress
in vitro blood flow model
Coumaronochromones, flavanones, and isoflavones from the twigs and leaves of Erythrina subumbrans inhibit PTP1B and nitric oxide production
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 206, 页码: 12
作者:
Liu, Cai-Ying
;
Deng, Pan
;
Wang, Bin
;
Liu, Ai-Hong
;
Wang, Meng-Ge
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/04/10
Erythrina subumbrans
Fabaceae
Sesquiterpenoids
Coumaronochromones
Flavanones
Isoflavones
Nitric oxide production inhibition
PTP1B inhibition
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Zhang, Chenlu
;
Liu, Yameng
;
Wang, Ying
;
Ge, Xie
;
Jiao, Tingying
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/11/11
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Zi-tong
;
Wang, Jue
;
Fang, Lei
;
Qian, Xin-di
;
Cai, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
nanoparticles
molecular targeted therapy
non-small cell lung cancer
dual-responsive
controlled release
Calysepins I-VII, Hexasaccharide Resin Glycosides from Calystegia sepium and Their Cytotoxic Evaluation
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2022, 卷号: 85, 期号: 5, 页码: 1294-1303
作者:
Lv, Kai-Qing
;
Ji, Hong-Ying
;
Du, Gao-Xiang
;
Peng, Shou
;
Guo, Peng-Ju
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16
作者:
Ge, Yiyue
;
Tian, Tingzhong
;
Huang, Suling
;
Wan, Fangping
;
Li, Jingxin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
The methyltransferase PRMT1 regulates γ-globin translation
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 卷号: 296, 页码: 100417
作者:
Wang, Ying
;
Li, Xinyu
;
Ge, Jingru
;
Liu, Ming
;
Pang, Xiaming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21