机构

• 上海药物研究所 [80]

采集方式

• OAI收割 [80]

内容类型

• 期刊论文 [80]

发表日期

• 2023 [7]
• 2022 [9]
• 2021 [8]
• 2020 [8]
• 2019 [4]
• 2018 [6]
• 更多

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浏览/检索结果: 共80条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891 作者:  Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 dihydrocelastrol  multiple myeloma  JAK2/STAT3  PSMB5  bortezomib resistance   Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9 作者:  Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Cytochrome P450 3A4 (CYP3A4)  Inhibitors  Isoquinoline chalcones  Orally active   Nanovesicles loaded with a TGF-& beta; receptor 1 inhibitor overcome immune resistance to potentiate cancer immunotherapy 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Zhou, Mengxue;  Wang, Jiaxin;  Pan, Jiaxing;  Wang, Hui;  Huang, Lujia   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 11 作者:  Li, Rui;  Zhang, Zherui;  Huang, Shuhong;  Peng, Ke;  Jiang, Hualiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 SARS-CoV-2  Niclosamide analogs  Cytotoxicity  Pharmacokinetic  SKP2 inhibition   Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565 作者:  Liu, Bo;  Yu, Xueni;  Liu, Liping;  Wang, Lei;  Wang, Jie   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 Acid-Ionizable Iron Nanoadjuvant Augments STING Activation for Personalized Vaccination Immunotherapy of Cancer 期刊论文  OAI收割 ADVANCED MATERIALS, 2023, 页码: 15 作者:  Chen, Fangmin;  Li, Tianliang;  Zhang, Huijuan;  Saeed, Madiha;  Liu, Xiaoying   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 acid-ionizable nanoadjuvants  cancer vaccines  iron oxide nanoparticles  personalized immunotherapy  STING cascade activation   Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 9 作者:  Huang, Jin-Chang   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/12/13 Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14 作者:  Sun, Haiguo;  Xi, Mengyu;  Jin, Qiang;  Zhu, Zhengdan;  Zhang, Yani   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/09/30 A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11 作者:  Zeng, Yue;  Shi, Wei;  Dong, Qian;  Li, Wanzhen;  Zhang, Jianxin   |  收藏  |  浏览/下载：53/0  |  提交时间：2022/08/30 Acyl Transfer  Anti-Tumor  One-Step Synthesis  Site-Specific ADCs  Thioester