中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [149]
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OAI收割 [149]
内容类型
期刊论文 [147]
会议论文 [2]
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2023 [9]
2022 [8]
2021 [10]
2020 [7]
2019 [9]
2018 [3]
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学科主题
Pharmacolo... [2]
Chemistry [1]
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浏览/检索结果:
共149条,第1-10条
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Elucidation of N-/O-glycosylation and site-specific mapping of sialic acid linkage isomers of SARS-CoV-2 human receptor angiotensin-converting enzyme 2
期刊论文
OAI收割
ANALYST, 2023, 卷号: 148, 期号: 20, 页码: 5002-5011
作者:
Wei, Liming
;
Chen, Yuning
;
Feng, Xiaoxiao
;
Yao, Jun
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2023, 页码: 8
作者:
Li, Jin-Long
;
Jiang, Jia-Yi
;
Gu, Shan-Shan
;
Zhang, Lei
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Pouzolzia zeylanica
lignans
ATP citrate lyase (ACLY) inhibitors
Enantiomeric pairs of macrocyclic acylphloroglucinols from Syzygium szemaoense
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 6
作者:
Huang, Jin-Chang
;
Hong Xu, Hong-
;
Shi, Qing
;
Lei, Chun
;
Li, Jing-Ya
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
Syzygium szemaoense
Acylphloroglucinol enantiomers
Death -associated protein kinase-related
apoptosis inducing protein kinase 2
ATP citrate lyase
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Xia, Bingqing
;
Pan, Xiaoyan
;
Luo, Rong-Hua
;
Shen, Xurui
;
Li, Shuangqu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Discovery and photosynthesis of sinuaustones A and B, diterpenoids with a novel carbon scaffold isolated from soft coral Sinularia australiensis from Hainan
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 8
作者:
Wu, Meng-Jun
;
Yu, Dan-Dan
;
Su, Ming-Zhi
;
Wang, Jian-Rong
;
Gong, Lei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/11