中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [65]
采集方式
OAI收割 [65]
内容类型
期刊论文 [65]
发表日期
2024 [1]
2023 [9]
2022 [9]
2021 [8]
2020 [8]
2019 [3]
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学科主题
Chemistry [1]
Pharmacolo... [1]
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浏览/检索结果:
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专题:上海药物研究所
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A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma
期刊论文
OAI收割
LEUKEMIA, 2023, 页码: 4
作者:
Xu, Li
;
Wang, Yingcong
;
Wang, Guanli
;
Guo, Shushan
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors
期刊论文
OAI收割
NATURE CHEMISTRY, 2023, 页码: 18
作者:
Guo, An-Di
;
Yan, Ke-Nian
;
Hu, Hao
;
Zhai, Linhui
;
Hu, Teng-Fei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Xia, Bingqing
;
Pan, Xiaoyan
;
Luo, Rong-Hua
;
Shen, Xurui
;
Li, Shuangqu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Flavonoids from the roots and rhizomes of Sophora tonkinensis and their in vitro anti-SARS-CoV-2 activity
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 1, 页码: 65
作者:
Li Zhuo
;
Xie Hang
;
Tang Chunping
;
Feng Lu
;
Ke Changqiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
Sophora tonkinensis
Flavonoid
Anti-SARS-CoV-2 activity
SARS-CoV-2 3CLpro
SARS-CoV-2 PLpro
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor