中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [60]
采集方式
OAI收割 [60]
内容类型
期刊论文 [59]
会议论文 [1]
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2023 [7]
2022 [7]
2021 [8]
2020 [3]
2019 [4]
2018 [5]
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment
Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 8, 页码: 17
作者:
Zhu, Hongwen
;
Lin, Youpei
;
Lu, Dayun
;
Wang, Shisheng
;
Liu, Yuejia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
proteomics
hepatocellular carcinoma
normal tissue adjacent to tumor
heterogeneity
ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571
作者:
Zhang, Yanqiong
;
Li, Xin
;
Shi, Yulong
;
Chen, Tong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Traditional Chinese medicine
Database
Target identification
Network visualization
New drug research and development
Molecular mechanism
Quality marker
Drug repurposing
Conjugation site characterization of antibody-drug conjugates using electron-transfer/higher-energy collision dissociation (EThcD)
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2023, 卷号: 1251, 页码: 7
作者:
Song, Yuanli
;
Gao, Jing
;
Meng, Qian
;
Tang, Feng
;
Wang, Yuqiu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Antibody -drug conjugates
EThcD
Conjugation site
Peptide mapping
Quality control
Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1737
作者:
Cheng, Ying
;
Lyu, Xilin
;
Liu, Chen
;
Wang, Xiancheng
;
Cheng, Jing
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
sclareolide
indole
polyphenol
acetal
antitumor activity
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 31
作者:
Lou, Jianfeng
;
Lu, Yuhang
;
Cheng, Jing
;
Zhou, Feilong
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/13
TEAD
YAP
Palmitoylation
Protein-protein interaction
Covalent inhibitor
Uncommon Capnosane Diterpenes with Neuroprotective Potential from South China Sea Soft Coral Sarcophyton boettgeri
期刊论文
OAI收割
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 14
作者:
Du, Ye-Qing
;
Chen, Jing
;
Wu, Meng-Jun
;
Zhang, Hai-Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/12/13
soft coral
Sarcophyton boettgeri
capnosane
absolute configuration
neuroprotective effect
Hypoxia-Activated PEGylated Paclitaxel Prodrug Nanoparticles for Potentiated Chemotherapy
期刊论文
OAI收割
ACS NANO, 2022, 页码: 10
作者:
Hao, Dengyuan
;
Meng, Qian
;
Jiang, Bowen
;
Lu, Shaojin
;
Xiang, Xiujuan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/11
PEGylation
prodrugs
self-assembly
hypoxia-responsive
paclitaxel