机构

• 上海药物研究所 [29]

采集方式

• OAI收割 [29]

内容类型

• 期刊论文 [29]

发表日期

• 2023 [2]
• 2022 [4]
• 2021 [4]
• 2020 [2]
• 2019 [9]
• 2018 [5]
• 更多

学科主题

筛选

浏览/检索结果: 共29条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割 LIFE SCIENCES, 2023, 卷号: 332, 页码: 10 作者:  Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 CD73  Proteasome inhibitors  ERK  NSCLC   Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割 MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798 作者:  Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/08/16 TPN171  [C-14]TPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Intestinal Glucuronidation, Prior to Hepatic Glucuronidation, Plays an Important Role in the Low Circulating Levels of Calycosin 期刊论文  OAI收割 SEPARATIONS, 2022, 卷号: 9, 期号: 5, 页码: 15 作者:  Jiang, Haodong;  Liu, Huan;  Hu, Pei;  Chen, Shuoji;  Ye, Yaqing   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 calycosin  first-pass effect  intestinal glucuronidation  liver distribution  metabolism   Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14 作者:  Wu, Qian;  Chen, Dan-Qi;  Sun, Lin;  Huan, Xia-Juan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：39/0  |  提交时间：2021/05/24 N2817  Bivalent BET inhibitors  Monovalent BET inhibitors  TAF1  Anticancer activity   Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文  OAI收割 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18 作者:     |  收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文  OAI收割 Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1 作者:  Ning Zhang;  Yu-Nan Tian;  Li-Na Zhou;  Meng-Zhu Li;  Hua-Dong Chen   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/12/01