中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
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OAI收割 [24]
内容类型
期刊论文 [23]
会议论文 [1]
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2023 [5]
2022 [4]
2021 [1]
2020 [1]
2018 [4]
2017 [2]
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专题:上海药物研究所
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Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5
作者:
Lian, Xuanmin
;
Gao, Yue
;
Li, Xuemei
;
Wang, Peipei
;
Tong, Lexian
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
2-aminopyrimidine
FLT3 inhibitors
MV4-11
FLT3 mutations
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Li, Xuemei
;
Wang, Peipei
;
Wang, Chang
;
Jin, Tingting
;
Xu, Ran
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Saliva as a noninvasive sampling matrix for therapeutic drug monitoring of intravenous busulfan in Chinese patients undergoing hematopoietic stem cell transplantation: A prospective population pharmacokinetic and simulation study
期刊论文
OAI收割
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2023, 页码: 12
作者:
Xu, Baohua
;
Yang, Ting
;
Zhou, Jianxing
;
Zheng, You
;
Wang, Jingting
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 15
作者:
Wang, YuKun
;
Li, Jing
;
Wu, Li
;
Qin, XueMei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
bile acids
enterohepatic circulation
FXR-related genes
saikosaponins
Microbial transformation of osthole by human intestinal fungi and anti-osteoporosis activities of its metabolites
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 167, 页码: 6
作者:
He, Xin
;
Nie, Min
;
Wang, Mengyuan
;
Wu, Shifei
;
Wei, Xuemei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Osthole
Microbial transformation
Mucor circinelloides
Anti -osteoporosis activity
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia
期刊论文
OAI收割
LEUKEMIA, 2022, 页码: 11
作者:
Jiang, Kailong
;
Li, Xuemei
;
Wang, Chang
;
Hu, Xiaobei
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer
Software Assisted Multi-Tiered Mass Spectrometry Identification of Compounds in Traditional Chinese Medicine: Dalbergia odorifera as an Example
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 7, 页码: 15
作者:
Wang, Mengyuan
;
Yao, Changliang
;
Li, Jiayuan
;
Wei, Xuemei
;
Xu, Meng
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/06/15
software
mass spectrometry
flavonoid
Dalbergia odorifera
Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248
作者:
Tong, Lexian
;
Wang, Peipei
;
Li, Xuemei
;
Dong, Xiaowu
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
An enhanced strategy integrating offline two-dimensional separation with data independent acquisition mode and deconvolution: Characterization of metabolites of Uncaria rhynchophylla in rat plasma as a case
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 8
作者:
Li, Haojv
;
Wei, Wenlong
;
Li, Zhenwei
;
Wang, Mengyuan
;
Wei, Xuemei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
Off-line 2D separation system
Metabolites characterization in vivo
Data independent acquisition
Multi-dimensional deconvolution
Uncaria rhynchophylla