中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
采集方式
OAI收割 [9]
内容类型
期刊论文 [9]
发表日期
2023 [3]
2022 [1]
2021 [1]
2020 [1]
2019 [1]
2018 [1]
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专题:上海药物研究所
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Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:
Xu, Zhijian
;
Shi, Danrong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/27
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Xia, Bingqing
;
Pan, Xiaoyan
;
Luo, Rong-Hua
;
Shen, Xurui
;
Li, Shuangqu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 7, 页码: 14
作者:
Lin, Jian
;
Dai, Yuting
;
Sang, Chen
;
Song, Guohe
;
Xiang, Bin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/08/30
tumor microenvironment
cytotoxicity
immunologic
drug therapy
combination
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/08/17
Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 卷号: 412, 期号: 13, 页码: 3241-3252
作者:
Zheng, Xiaoli
;
Duan, Haonan
;
Lin, Feifei
;
Li, Xiaomei
;
Shen, Jianhua
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/01
Phenols
Aromatic acid
Microbiota
Uremic toxin
Simultaneous derivatization
2-Bromo-1-[4-(dimethylamino)phenyl] ethyl ketone
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Zhen
;
Jiang, Xiangrui
;
Zhang, Xianglei
;
Tian, Guanghui
;
Yang, Rulei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53
期刊论文
OAI收割
CANCER RESEARCH, 2018, 卷号: 78, 期号: 13, 页码: 3484-3496
作者:
Mao, Chao
;
Wang, Xiang
;
Liu, Yating
;
Wang, Min
;
Bin Yan
  |  
收藏
  |  
浏览/下载:127/0
  |  
提交时间:2019/01/08
Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 2, 页码: 958-962
作者:
Huang, Huang
;
Lu, Weiqiang
;
Li, Xi
;
Cong, Xiaoli
;
Ma, Hongmei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Falcipain-2
Dihydrofolate reductase
Dual inhibitor
Antimalarial drug
SAR
Molecular docking