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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng
  |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:  Lin, Ting-ting;  Xiong, Wei;  Chen, Gui-hua;  He, Yang;  Long, Li
  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26
Versatile Biocatalytic C(sp(3))-H Oxyfunctionalization for the Site- Selective and Stereodivergent Synthesis of & alpha;- and & beta;-Hydroxy Acids 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 9
作者:  Mao, Yingle;  Zhang, Weijie;  Fu, Zunyun;  Liu, Yanqiong;  Chen, Lin
  |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17
A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function 期刊论文  OAI收割
CELL REPORTS PHYSICAL SCIENCE, 2022, 卷号: 3, 期号: 10, 页码: 12
作者:  Xu, Yan;  Fu, Dingqiang;  Yuan, Yi;  Peng, Yan;  Dong, Juan
  |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10
Multi-omics analysis reveals the pathogenesis of db/db mice diabetic kidney disease and the treatment mechanisms of multi-bioactive compounds combination from Salvia miltiorrhiza 期刊论文  OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 16
作者:  Xu, Zhuo;  Xiang, Xiang;  Su, Shulan;  Zhu, Yue;  Yan, Hui
  |  收藏  |  浏览/下载：36/0  |  提交时间：2022/12/13
Therapeutic potential of traditional Chinese medicine for the treatment of NAFLD: A promising drug Potentilla discolor Bunge 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 9, 页码: 3529-3547
作者:  Ji, Longshan;  Li, Qian;  He, Yong;  Zhang, Xin;  Zhou, Zhenhua
  |  收藏  |  浏览/下载：20/0  |  提交时间：2022/12/13
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18, 期号: 4, 页码: 1594-1611
作者:  Li, Qian;  Tan, Jia-Xin;  He, Yong;  Bai, Fang;  Li, Shi-Wei
  |  收藏  |  浏览/下载：24/0  |  提交时间：2022/06/15
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 11, 页码: 1913-1920
作者:  Ou, An-te;  Zhang, Jia-xin;  Fang, Yue-fei;  Wang, Rong;  Tang, Xue-ping
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/21
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan
  |  收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04
Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats 期刊论文  OAI收割
NEUROSCIENCE BULLETIN, 2020, 卷号: 36, 期号: 4, 页码: 333-345
作者:  Gu, Pan;  Xu, Zi-Hao;  Cao, Yu-Ze;  Liao, Sheng-Hui
  |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01