中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [235]
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:  
Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si
  |  收藏  |  浏览/下载:16/0  |  提交时间:2024/03/25
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:  
Lin, Ting-ting;  Xiong, Wei;  Chen, Gui-hua;  He, Yang;  Long, Li
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/01/26
Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文  OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:  
Wang, Yafang;  Yao, Mingyue;  Li, Cheng;  Yang, Kexin;  Qin, Xiaolong
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/01/26
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:  
Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/02/27
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:  
Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan
  |  收藏  |  浏览/下载:58/0  |  提交时间:2023/10/17
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment 期刊论文  OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:  
Ding, Mengyuan;  Shen, Qianqian;  Lu, Wei;  Zhu, Shulei
  |  收藏  |  浏览/下载:62/0  |  提交时间:2023/10/17
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:  
Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin
  |  收藏  |  浏览/下载:24/0  |  提交时间:2023/10/17
Smart drug delivery systems to overcome drug resistance in cancer immunotherapy 期刊论文  OAI收割
CANCER BIOLOGY & MEDICINE, 2023, 卷号: 20, 期号: 4, 页码: 248-267
作者:  
Yi, Wenzhe;  Yan, Dan;  Wang, Dangge;  Li, Yaping
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria 期刊论文  OAI收割
CHEMMEDCHEM, 2023, 卷号: 18, 期号: 9
作者:  
Guan, Dongliang;  Chen, Feifei;  Shi, Wei;  Lan, Lefu;  Huang, Wei
  |  收藏  |  浏览/下载:4/0  |  提交时间:2024/03/27
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead 期刊论文  OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:  
Li, Hui-yu;  Qi, Wei-liang;  Wang, Yu-xiang;  Meng, Ling-hua
  |  收藏  |  浏览/下载:117/0  |  提交时间:2023/10/17