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浏览/检索结果: 共275条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Optimization design of optical windows for deep-sea pressure-resistant structures based on transition materials 期刊论文  OAI收割 FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 13 作者:  Wei, Yucong;  Ma, Guoliang;  Zhang, Hailong;  Zhang, Xiaowei;  Quan, Xiangqian   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/02/06 pressure-resistant structure  optical window design  finite element analysis  mechanical model analysis  optimized design scheme   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Design and Analysis of High Temperature Superconducting Current Leads for CRAFT TF Magnet 期刊论文  OAI收割 IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 2023, 卷号: 33 作者:  Han, Quan;  Lu, Kun;  Song, Yuntao;  Ding, Kaizhong;  Liu, Chen   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/11/10 Analysis  Comprehensive Research Facility for Fusion Technology (CRAFT)  high-temperature superconducting current leads (HTSCL)  structure design  toroidal field (TF) magnet   Wavy interface enables extra strengthening in an additively manufactured high-entropy alloy with Mortise-Tenon architecture 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PLASTICITY, 2023, 卷号: 170, 页码: 18 作者:  Bai, Yunjian;  Li, Yadong;  Wang, Yun-jiang;  Zhang, Kun;  Jiang, Quanyu   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/18 High entropy alloy  Laminated structure design  Additive manufacturing  Interface strengthening  Local chemical variation   Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   Catalytic oxidation properties of 3D printed ceramics with Bouligand structures 期刊论文  OAI收割 Chemical Engineering Journal, 2023, 卷号: 474, 期号: 无, 页码: 145504 作者:  Xu X(徐昕);  He B(何波);  Wang YX(汪祎贤);  Xi YT(席云泰);  Liu DS(刘德胜)   |  收藏  |  浏览/下载：73/0  |  提交时间：2023/10/31 Bioinspired structural design  3D printing  Bouligand structure  Helicoidal catalytic ceramics  VOCs catalytic oxidation   Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958 作者:  Ge, Haixia;  Ji, Beihong;  Fang, Jiahui;  Wang, Jiayang;  Li, Jing   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 function-based ligand design  receptor-ligandbinding profile  CB1/CB2  structure-activityrelationship   Catalytic oxidation properties of 3D printed ceramics with Bouligand structures 期刊论文  OAI收割 Chemical Engineering Journal, 2023, 期号: 474, 页码: 145504 作者:  Xin Xu;  Bo He;  Yixian Wang;  Yuntai Xi;  Desheng Liu   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/01/02 Bioinspired structural design  3D printing  Bouligand structure  Helicoidal catalytic ceramics  VOCs catalytic oxidation