机构

• 上海药物研究所 [53]

采集方式

• OAI收割 [53]

内容类型

• 期刊论文 [53]

发表日期

• 2023 [53]

学科主题

筛选

浏览/检索结果: 共53条，第1-10条 帮助 限定条件 发表日期：2023    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 260, 页码: 14 作者:  Jiang, Zhiyang;  Shi, Dongmei;  Chen, Yitong;  Li, Huilin;  Wang, Jin 'e   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Rice blast  Trehalose-6-phosphate synthase  Isopropanolamine compounds  Inhibitor  Fungicidal mechanism   Enhancing physical and chemical stability of hygroscopic hydroxytyrosol by cocrystal formation 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 646, 页码: 8 作者:  Zhu, Bingqing;  Xia, Mengyuan;  Ding, Zhenfeng;  Rong, Xiaoyi;  Mei, Xuefeng   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 Hydroxytyrosol  Cocrystal  Solidification  Hygroscopicity  Stability   Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28 作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/19 MLL-rearranged leukemia  super elongation complexes  small-molecule inhibitor  protein-protein interaction  cancer therapeutics   Discovery of novel cGAS inhibitors based on natural flavonoids 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 14 作者:  Li, Jiameng;  Xiong, Muya;  Liu, Jiayuan;  Zhang, Fengping;  Li, Minjun   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cyclic GMP-AMP synthase  Inhibitor  Flavonoids  Crystal structure  Virtual screening   Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil 期刊论文  OAI收割 NEUROSCIENCE BULLETIN, 2023, 页码: 15 作者:  Wu, Peng-Peng;  Cao, Bi-Rong;  Tian, Fu-Yun;  Gao, Zhao-Bing   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Levetiracetam  Epilepsy  Antiseizure medications  Synaptic vesicle protein 2A  Brivaracetam  Padsevonil   Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach   A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2023, 页码: 14 作者:  Wang, Yunxia;  Pan, Ziqi;  Mou, Minjie;  Xia, Weiqi;  Zhang, Hongning   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9 作者:  Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/08 Cytochrome P450 3A4 (CYP3A4)  Inhibitors  Isoquinoline chalcones  Orally active