中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Structurally diverse terpenoids and their DRAK2 inhibitory activities: A follow-up study on the vulnerable conifer Pseudotsuga forrestii
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1305, 页码: 13
作者:
Zhou, Peng-Jun
;
Huang, Ting
;
Ma, Guang-Lei
;
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Pseudotsuga forrestii
Rare and endangered plants (REPs)
Triterpene-monoterpene hybrids
GLMDs
DRAK2 inhibition
Molecular docking
A Computational and Chemical Design Strategy for Manipulating Glycan-Protein Recognition
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Zhu, Qiang
;
Geng, Didi
;
Li, Jingchao
;
Zhang, Jinqiu
;
Sun, Haofan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
CH-pi interaction
glycan-protein recognition
glycoproteomics
PhoSL
core fucose
Expeditious Synthesis of Gwanakoside A and the Chloronaphthol Glycoside Congeners
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 12, 页码: 2425-2429
作者:
Cheng, Yuting
;
Xia, Yan
;
Yuan, Ziqi
;
Li, Haotian
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16
作者:
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Benzimidazole-chitosan quaternary ammonium
salt
Nanogels
pH-responsive
Antioxidant activity
Antitumor activity
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Design, Synthesis, and Structure-Activity Relationship of Novel Potent and Highly Selective Cysteinyl Leukotriene Receptor 1 (CysLT1R) Antagonists
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 1, 页码: 259-276
作者:
Wang Jingyi
;
Liu Jinyu
;
Chen Dongsheng
;
Chen Huayan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
cysteinyl leukotriene
cysteinyl leukotriene receptor 1 (CysLT1R)
selective antagonists
Self-assembled low molecular weight chitosan-based cationic micelle for improved water solubility, stability and sustained release of & alpha;-tocopherol
期刊论文
OAI收割
FOOD CHEMISTRY, 2023, 卷号: 429, 页码: 11
作者:
Yuan, Yuting
;
Wang, Zhenhua
;
Su, Shengjia
;
Lin, Conghao
;
Mi, Yingqi
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Amphiphilic low molecular weight chitosan derivative
Photostability
Self-assembled cationic micelle
Solubility
Sustained release behavior
& alpha
-tocopherol