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Chinese Academy of Sciences Institutional Repositories Grid
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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1—28
作者:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
  |  
收藏
  |  
浏览/下载:418/0
  |  
提交时间:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
Kadcoccinoids A-K, triterpenoids from
Kadsura coccinea
with PCSK9 expression inhibitory activities
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 238, 页码: 13
作者:
Duan, Yelin
;
Chen, Tong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Kadsura coccinea
Schisandraceae
Lanostane-type triterpenoids
Protostane-type triterpenoids
PCSK9
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:
Tian, Lina
;
Xiao, Jian
;
Zeng, Yanping
;
Li, Yangsha
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CDK9
EZH2
Dual target inhibitor
DLBCL
Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16
作者:
Chen, Sumeng
;
Huang, Jindi
;
Zhang, Shipeng
;
Zheng, Xinni
;
Chen, Hongming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/23
CDK9
Inhibitor
Acute myeloid leukemia
Binding mode
Cellular mechanism
4, 9-dihydroxy-α-lapachone as a potent antiproliferation agent for triple-negative breast cancer
via
ferroptosis
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 183, 页码: 10
作者:
He, Zhong
;
Long, Hui
;
Ma, Hongyue
;
Ran, Wanrong
;
Song, Yinhong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/25
4, 9-dihydroxy-alpha-lapachone
Ferroptosis
TNBC
GPX4
First ATG101-recruiting small molecule degrader for selective CDK9 degradation
via
autophagy-lysosome pathway
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624
作者:
Zhong, Ye
;
Xu, Jing
;
Cao, Huiying
;
Gao, Jie
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
Protein degradation
Hydrophobic tags
ATG101
Autophagy-lysosome pathway
CDK9
Cyclin T1
Degrader
Antitumor
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Nano-Polymers as Cas9 Inhibitors
期刊论文
OAI收割
POLYMERS, 2025, 卷号: 17, 期号: 3, 页码: 16
作者:
Chepurna, Oksana
;
Chatterjee, Avradip
;
Li, Yuanqing
;
Ding, Hong
;
Murali, Ramachandran
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/04/01
CRISPR/Cas9
nano-polymer
inhibitor
polymalic acid
polyglutamic acid
polyaspartic acid
trileucine
Rubiadin Mediates the Upregulation of Hepatic Hepcidin and Alleviates Iron Overload via BMP6/SMAD1/5/9-Signaling Pathway
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 卷号: 26, 期号: 3, 页码: 14
作者:
Xie, Xueting
;
Chang, Linyue
;
Zhu, Xinyue
;
Gong, Fengbei
;
Che, Linlin
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/04/01
rubiadin
hepcidin
iron metabolism
iron overload
BMP6/SMAD1/5/9-signaling pathway
A comparative analysis of five land surface temperature downscaling methods in plateau mountainous areas
期刊论文
OAI收割
FRONTIERS IN EARTH SCIENCE, 2025, 卷号: 12, 页码: 1488711
作者:
Wang, Ju
;
Tang, Bo-Hui
;
Zhu, Xinming
;
Fan, Dong
;
Li, Menghua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/02/24
land surface temperature
downscaling
Landsat-9
machine learning
XGBoost