中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
水生生物研究所 [3]
大连化学物理研究所 [2]
生态环境研究中心 [2]
广州地球化学研究所 [1]
上海营养与健康研究所 [1]
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OAI收割 [16]
内容类型
期刊论文 [16]
发表日期
2023 [1]
2022 [3]
2021 [1]
2019 [1]
2018 [2]
2017 [1]
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学科主题
Fisheries;... [2]
Life Scien... [1]
Nutrition ... [1]
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In vitro hepatic metabolism of polychlorinated biphenyls with different chlorine-substituted structures in rats and humans: Kinetics, metabolism, and potential nuclear receptor affinities
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 864, 页码: 10
作者:
Huang, Chenchen
;
Hu, Keqi
;
Zeng, Yanhong
;
Jiang, Yiye
;
Tian, Yankuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/21
Hepatic metabolism
Polychlorinated biphenyls
Human
Rat
Nuclear receptor affinities
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Insights into the toxicokinetic, tissue distribution and maternal transfer of polychlorinated dibenzo-p-dioxins/dibenzofurans in laying hens fed with dioxin-associated dietary
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 816, 期号: 0, 页码: 151664
作者:
Wang, Chu
;
Dong, Shujun
;
Wang, Pu
;
Hao, Yanfen
;
Wang, Ruiguo
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/08
CONGENER-SPECIFIC METABOLISM
BIPHENYLS PCBS
HEPATIC SEQUESTRATION
COMMON CORMORANTS
FLAME RETARDANTS
LAKE BIWA
PCDD/FS
EGGS
BIOACCUMULATION
RESIDUES
Double-edge sword roles of iron in driving energy production versus instigating ferroptosis
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 1, 页码: 40
作者:
Zhang, Shuping
;
Xin, Wei
;
Anderson, Gregory J.
;
Li, Ruibin
;
Gao, Ling
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/11/08
HEPATIC GLUCOSE-PRODUCTION
FATTY-ACID OXIDATION
CELL-DEATH
PARKINSONS-DISEASE
DIABETES-MELLITUS
METABOLISM
TUMOR
MITOCHONDRIA
HOMEOSTASIS
DEFICIENCY
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
OAI收割
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice
期刊论文
OAI收割
TOXICOLOGY IN VITRO, 2018, 卷号: 46, 页码: 1-8
作者:
Li, Zhongyu
;
Jiang, Lei
;
Zhu, Yujuan
;
Su, Wentao
;
Xu, Cong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/06/20
Microfluidics
Drug Testing
Hepatic Metabolism
Nephrotoxicity
Organs-on-a-chip
Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet
期刊论文
OAI收割
NUTRIENTS, 2017, 卷号: 9, 期号: 8, 页码: 805
作者:
Luan, Yi
;
Zhang, Fang
;
Cheng, Yalan
;
Liu, Jun
;
Huang, Rui
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/09
hemin
insulin resistance
lipid metabolism
hepatic steatosis
Dietary manganese requirement of juvenile yellow catfish Pelteobagrus fulvidraco, and effects on whole body mineral composition and hepatic intermediary metabolism
期刊论文
OAI收割
AQUACULTURE, 2012, 卷号: 326, 期号: -, 页码: 68-73
作者:
Tan, Xiao-Ying
;
Xie, Ping
;
Luo, Zhi
;
Lin, Hei-Zhao
;
Zhao, Yan-Hong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2012/09/25
Growth Performance
Hepatic Intermediary Metabolism
Mineral Composition
Pelteobagrus Fulvidraco
Manganese Requirement