机构

• 上海药物研究所 [4]
• 金属研究所 [1]
• 西双版纳热带植物园 [1]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2023 [2]
• 2021 [1]
• 2020 [1]
• 2018 [2]
• 2012 [1]

学科主题

• Chemistry [1]
• Pharmacolo... [1]
• Plant Scie... [1]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14 作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/01/16 Phosphodiesterase-4 (PDE4)  PDE5  Inhibitor  Drug repurposing  Crystal structure  Structure -guided optimization   Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 124, 页码: 108567 作者:  Ma,Rui;  Song,Na;  Wang,Lveli;  Gu,Xi;  Xiong,Feng   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/07/22 PHOSPHODIESTERASE-4 INHIBITOR  ACCURATE DOCKING  APREMILAST  EFFICACY  INSIGHTS  DISEASE  ASTHMA  POTENT  GLIDE   PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7 期刊论文  OAI收割 FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12 作者:  Huang, Zhengnan;  Liu, Jiakuan;  Yang, Jiale;  Yan, Yilin;  Yang, Chenkai   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/06/15 phosphodiesterase 4B  urinary bladder cancer  chromobox protein homolog 7  epithelial-to-mesenchymal transition  beta-catenin   Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文  OAI收割 MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15 作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/12/24 Salt-inducible kinase 1  Phanginin A  Phosphodiesterase 4  Gluconeogenesis  cAMP   Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Li, Heng;  Zuo, Jianping;  Tang, Wei   |  收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08 phosphodiesterase-4  psoriasis  atopic dermatitis  inflammatory airway diseases  inflammatory bowel  disease  roflumilast  apremilast  crisaborole   A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata 期刊论文  OAI收割 JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 12, 页码: 1123-1128 作者:  Liu, Xin;  Tang, Gui-Hua;  Weng, Han-Zhuang;  Zhang, Jun-Sheng;  Xu, You-Kai   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/04/22 Phosphodiesterase-4 Inhibitors  Natural Pigment  Tamariscina   Association of inflammatory response gene polymorphism with atherothrombotic stroke in Northern Han Chinese 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2012, 卷号: 44, 期号: 12, 页码: 1023-1030 作者:     |  收藏  |  浏览/下载：37/0  |  提交时间：2021/02/02 5-LIPOXYGENASE ACTIVATING PROTEIN  CAROTID-ARTERY ATHEROSCLEROSIS  ISCHEMIC-STROKE  PHOSPHODIESTERASE 4D  MYOCARDIAL-INFARCTION  CEREBRAL INFARCTION  ALOX5AP GENE  PDE4D GENE  POPULATION  RISK  inflammation  polymorphism  atherothrombotic stroke  ALOX5AP  PDE4D