机构

• 上海药物研究所 [13]
• 海洋研究所 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2024 [1]
• 2023 [1]
• 2021 [1]
• 2018 [2]
• 2015 [1]
• 2013 [2]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9 作者:  Tuohongerbieke, Amanguli;  Liu, Liu;  Li, Jun;  Xin, Xuelei;  Aisa, Haji Akber   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 Limonium gmelinii (Willd  ) Kuntze  Plumbaginaceae  Lignanamides  Protein tyrosine phosphatase 1B inhibitors  PI3K  AKT Signaling Pathway   Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13 作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/05/11 Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities   Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 11 作者:  Wang, Xiao-Hang;  Zhu, Ke-Xin;  Li, Jing-Ya;  Lei, Chun;  Hou, Ai-Jun   |  收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08 Dodonaea viscosa  vistriterpenoids A and B  triterpenoids  protein tyrosine phosphatase 1b (PTP1B)  PTP1B inhibitors  inhibitory activity   Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 692-700 作者:  Du, Yongli;  Zhang, Yanhui;  Ling, Hao;  Li, Qunyi;  Shen, Jingkang   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitors  N-(2,5-diethoxy-phenyl)-methane sulfonamide  Type 2 diabetes mellitus  PTP1B   Synthesis of Novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene Derivatives and Their Biological Evaluation Against Protein Tyrosine Phosphatase 1B 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 5, 页码: 1161-1167 作者:  Wang, Wen-Long;  Chen, Xia;  Gao, Li-Xin;  Sheng, Li;  Li, Jing-Ya   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene derivatives  inhibitors  one-pot synthesis  protein tyrosine phosphatase 1B  structure-activity relationships   Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2013, 卷号: 28, 期号: 6, 页码: 1199-1204 作者:  Sun, Liang-Peng;  Ma, Wei-Ping;  Gao, Li-Xin;  Yang, Ling-Ling;  Quan, Ying-Chun   |  收藏  |  浏览/下载：68/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B  inhibitors  5,7-dihydroxyflavanone  structure-activity relationship  diabetes   Synthesis and Biological Evaluation of Furan-chalcone Derivatives as Protein Tyrosine Phosphatase Inhibitors 期刊论文  OAI收割 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2013, 卷号: 34, 期号: 4, 页码: 1023-1024 作者:  Sun, Liang-Peng;  Jiang, Zhe;  Goo, Li-Xin;  Sheng, Li;  Quan, Ying-Chun   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B  Inhibitors  Furan-chalcone  SAR   Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 24, 页码: 7440-7443 作者:  Dai, Hou-ling;  Gao, Li-xin;  Yang, Ying;  Li, Jing-ya;  Cheng, Jia-gao   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B  Molecular docking  Inhibitors  Di-indolinone   Synthesis and Biological Evaluation of 2,4,6-Trihydroxychalcone Derivatives as Novel Protein Tyrosine Phosphatase 1B Inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2012, 卷号: 80, 期号: 4, 页码: 584-590 作者:  Sun, Liang-Peng;  Gao, Li-Xin;  Ma, Wei-Ping;  Nan, Fa-Jun;  Li, Jia   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 2  4  6-trihydroxychalcone  diabetes  inhibitors  protein tyrosine phosphatase 1B  structure-activity relationship