中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
近代物理研究所 [1]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2023 [1]
2022 [1]
2018 [1]
2016 [1]
2015 [1]
2014 [2]
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Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Remodeling "cold" tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 2057-2073
作者:
He, Yang
;
Fang, Yuefei
;
Zhang, Meng
;
Zhao, Yuge
;
Tu, Bin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
Tumor immune microenvironment
Tumor-associated macrophage
Epigenetic therapy
Immune checkpoint
Angiogenesis
Panobinostat
JQ1
Liposome
Epigenetic actions of environmental factors and promising drugs for cancer therapy (Review)
期刊论文
OAI收割
ONCOLOGY LETTERS, 2018, 卷号: 15, 页码: 2049-2056
作者:
Bai, Zhong-Tian
;
Bai, Bing
;
Zhu, Jun
;
Di, Cui-Xa
;
Li, Xun
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2018/05/31
epigenetic modification
environmental factor
promising drug
cancer therapy
DNA methyltransferase inhibitors: an updated patent review (2012-2015)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 9, 页码: 1017-1030
作者:
Xu, Pan
;
Hu, Guang
;
Luo, Cheng
;
Liang, Zhongjie
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
DNMT inhibitors (DNMTi)
epigenetic therapy
nucleotide derivatives
drug combination
allosteric inhibitor
Interaction Between DNA/histone Methyltransferases and their Inhibitors
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2015, 卷号: 22, 期号: 3, 页码: 360-372
作者:
Hu, J.
;
Chen, S.
;
Kong, X.
;
Zhu, K.
;
Cheng, S.
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
DNA methyltransferase
drug discovery
epigenetic therapy
histone methyltransferase
inhibitor
EZH2: biology, disease, and structure-based drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 161-174
作者:
Tan, Jin-zhi
;
Yan, Yan
;
Wang, Xiao-xi
;
Jiang, Yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
EZH2
PRC2
transcriptional repression
gene activation
anticancer drug
crystal structure
SET domain
methyltransferase inhibitor
epigenetic therapy
ezh2biologydiseaseandstructurebaseddrugdiscovery
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 161
作者:
Tan Jinzhi
;
Yan Yan
;
Wang Xiaoxi
;
Jiang Yi
;
Xu H Eric
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
EZH2
PRC2
transcriptional repression
gene activation
anticancer drug
crystal structure
SET domain
methyltransferase inhibitor
epigenetic therapy