中国科学院机构知识库网格
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Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Osman, Ezzat E. A.
;
Wang, Xiao-Juan
;
Choo, Yeun-Mun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Cryptotanshinone regulates gut microbiota and PI3K-AKT pathway in rats to alleviate CUMS induced depressive symptoms
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 169, 页码: 11
作者:
Bian, Li-hua
;
Wang, Si-qi
;
Li, Wen-jing
;
Li, Jie
;
Yin, Yi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/18
Depression
Cryptotanshinone
16 S rDNA
Transcriptomics
PI3K-AKT pathway
MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules
期刊论文
OAI收割
JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42
作者:
Liu, Xiaohong
;
Zhang, Wei
;
Tong, Xiaochu
;
Zhong, Feisheng
;
Li, Zhaojun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
De novo molecule design
Generative models
Deep learning
Virtual screening
Compound quality control
Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds
期刊论文
OAI收割
NATURE PLANTS, 2023, 卷号: 9, 期号: 4, 页码: 605-+
作者:
Lin, Jia-Ling
;
Fang, Xin
;
Li, Jian-Xu
;
Chen, Zhi-Wen
;
Wu, Wen-Kai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9
作者:
Tuohongerbieke, Amanguli
;
Liu, Liu
;
Li, Jun
;
Xin, Xuelei
;
Aisa, Haji Akber
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
Limonium gmelinii (Willd
) Kuntze
Plumbaginaceae
Lignanamides
Protein tyrosine phosphatase 1B inhibitors
PI3K
AKT Signaling Pathway
Pseudotargeted Metabolomics Approach Enabling the Classification-Induced Ginsenoside Characterization and Differentiation of Ginseng and Its Compound Formulation Products
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 页码: 13
作者:
Wang, Xiaoyan
;
Jiang, Meiting
;
Lou, Jia
;
Zou, Yadan
;
Liu, Meiyu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
ginseng
ginsenoside
triple quadrupole-linear ion trap mass spectrometry
classified identification
pseudotargeted metabolomics
identification marker
Geographical equations of Swertia mussotii bioactivities: evidence from the western Sichuan region of China
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14
作者:
Wang, Xiaobo
;
Shen, Cheng
;
Chen, Tao
;
Zhou, Xiaodan
;
Li, Yulin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/01
Generation of CRISPR/Cas9-mediated mutants in Monochasma savatieri using a hairy root system
期刊论文
OAI收割
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 191
作者:
Bai, Chen
;
Cao, Yingping
;
Zhao, Siyi
;
Wu, Zhenying
;
Dai, Shaojun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/01
Arylnaphthalide lignans from Saussurea medusa and their anti-inflammatory activities
期刊论文
OAI收割
ARABIAN JOURNAL OF CHEMISTRY, 2022, 卷号: 15, 期号: 10, 页码: 11
作者:
Cao, Jing-Ya
;
Dong, Qi
;
Wang, Zhi-Yao
;
Zhao, Ye
;
Ren, Yu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/13
Saussurea medusa
Arylnaphthalide lignan
Anti-inflammatory activity
ECD calculation
Molecular docking
Integrating UPLC-HR-MS/MS, Network Pharmacology, and Experimental Validation to Uncover the Mechanisms of Jin?gan Capsules against Breast Cancer br
期刊论文
OAI收割
ACS OMEGA, 2022, 卷号: 7, 期号: 32, 页码: 28003-28015
作者:
Qiu, Jianfei
;
Zhang, Zhiyin
;
Hu, Anling
;
Zhao, Peng
;
Wei, Xuenai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/30