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学科主题

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浏览/检索结果: 共487条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 初级体感皮层编码疼痛感知神经机制 学位论文  OAI收割 中国科学院心理研究所: 中国科学院大学, 2023 作者:  包充宇   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/02 疼痛感知  初级体感皮层  锥体神经元  中间神经元  神经机制   Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators 期刊论文  OAI收割 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868 作者:  Wang, Yun-Qi;  Guan, Zi-Yue;  Gao, Zhao-Bing;  Zheng, Yue-Ming   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/04/09 TRPM7  ion channel  physiological function  disease  small molecule modulators   Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28 作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 MLL-rearranged leukemia  super elongation complexes  small-molecule inhibitor  protein-protein interaction  cancer therapeutics   Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15 作者:  Jing, Shisuo;  Chen, Huayuan;  Liu, Ergang;  Zhang, Meng;  Shen, Huan   |  收藏  |  浏览/下载：89/0  |  提交时间：2023/10/17 Inflammatory bowel disease  Quercetin  colon-targeted delivery  Pectin microsphere  Oligochitosan  Immune microenvironment   Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer 期刊论文  OAI收割 PHYTOMEDICINE, 2023, 卷号: 114, 页码: 18 作者:  Zhao, Peng;  Qiu, Jianfei;  Pan, Chaolan;  Tang, Yunyan;  Chen, Meijun   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/10/17 Curcumae Rhizoma  Breast cancer  Chemoresistance  Metastasis  Curcumin   ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213 作者:  Sun, Nannan;  Yu, Mingcheng;  Jiang, Zhengyuan;  Yang, Feng;  Lu, Lixue   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 ROR?t agonists  Carbazole carboxamide  Agonistic activity  Metabolic stability  Co-crystallization  Molecular docking   Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Wang, Qiao-qiao;  Wang, Long;  Zhang, Wen-bo;  Tang, Chun-ping;  Chen, Xue-qin   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 Nav1.7 channel  naphthylisoquinolines  Ancistrocladus tectorius  dorsal root ganglion neurons  formalin-induced mouse inflammatory pain model  analgesics   Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11 作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 COVID-19  traditional Chinese medicine  TCMT-NDRD  antivirus  anti-inflammation