机构

• 上海药物研究所 [9]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2023 [4]
• 2022 [2]
• 2021 [2]
• 2020 [1]

学科主题

筛选

浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 9 作者:  Li, Rui;  Chen, Lin;  He, Xinheng;  Cao, Duanhua;  Zhang, Zehong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 10 作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 STING  CDN  Benzo[b]thiophene-2-carboxamide  Cellular activity   Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9 作者:  Shen, Chang;  Xu, Peijia;  Zhang, Changfa;  Su, Zhaoming;  Shan, Bin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 cGAS-STING signaling pathway  STING agonists  antitumor immunity  anti-infection immunity   Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034 作者:  Song, Shukai;  Tang, Haotian;  Ran, Ting;  Fang, Feng;  Tong, Linjiang   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 SyntaLinker  Generative modelling  TBK1 inhibitor  pyrrolo[2  3-d]pyrimidine  Structure-activity relationship   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 16 作者:  Niu, Jing;  Bai, Hudagula;  Li, Zizhou;  Gao, Yuzhe;  Zhang, Yan   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 STING  cGAS  Non-cyclic dinucleotides (non-CDNs)  Systemic administration  Antitumor immunotherapy   TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery 期刊论文  OAI收割 DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455 作者:  Xiang, Shuang;  Song, Shukai;  Tang, Haotian;  Smaill, Jeff B.;  Wang, Aiqun   |  收藏  |  浏览/下载：35/0  |  提交时间：2021/12/01 Antibiotic resistance  Computational biology  Databases  In silico tools   Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11 作者:  Bao, Weilian;  Liu, Xiaohong;  You, Yan;  Hou, Hui;  Wang, Xu   |  收藏  |  浏览/下载：64/0  |  提交时间：2021/11/24 SNX10  IBD  Macrophage  PIKfyve  TBK1  PPI inhibitor   Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者:  Ding, Chunyong;  Song, Zilan;  Shen, Ancheng;  Chen, Tingting;  Zhang, Ao   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 Immunotherapy  Anti-tumor  cGAS  STING  TBK1  Small molecule modulators