中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [40]
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  • 2023 [40]
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浏览/检索结果: 共40条，第1-10条 帮助

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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19
DNA Aptamer Binding Octapeptide Repeat Region of Cellular Prion Protein 期刊论文  OAI收割
ANALYTICAL CHEMISTRY, 2023, 卷号: 95, 期号: 50, 页码: 18595-18602
作者:  Sheng, Jing;  Zhang, Nan;  Long, Zhenhao;  Zhang, Xiangru;  Zu, Shuang
  |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu
  |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:  Wang, Jingyi;  Lin, Jianbang;  Chen, Yefei;  Liu, Jing;  Zheng, Qiongping
  |  收藏  |  浏览/下载：34/0  |  提交时间：2024/01/16
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model 期刊论文  OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:  Chen, Yefei;  Hong, Zexuan;  Wang, Jingyi;  Liu, Kunlin;  Liu, Jing
  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:  Xie, Chenghu;  Liu, Bo;  Song, Zilan;  Yang, Ye;  Dai, Mengdi
  |  收藏  |  浏览/下载：16/0  |  提交时间：2024/02/27
SGF29 nuclear condensates reinforce cellular aging 期刊论文  OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 21
作者:  Yan, Kaowen;  Ji, Qianzhao;  Zhao, Dongxin;  Li, Mingheng
  |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/11
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease 期刊论文  OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:  Jing, Shisuo;  Chen, Huayuan;  Liu, Ergang;  Zhang, Meng;  Shen, Huan
  |  收藏  |  浏览/下载：89/0  |  提交时间：2023/10/17
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16
作者:  Li, Yue;  Lv, Mengjia;  Shen, Meiling;  Gu, Xi;  Zhang, Li
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17