中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [46]
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OAI收割 [46]
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期刊论文 [46]
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2022 [6]
2021 [5]
2020 [4]
2019 [5]
2018 [6]
2016 [2]
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内容类型:期刊论文
专题:上海药物研究所
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Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
The progressive application of single-cell RNA sequencing technology in cardiovascular diseases
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 154, 页码: 14
作者:
Ke, Yang
;
Jian-yuan, Huang
;
Ping, Zhou
;
Yue, Wang
;
Na, Xing
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/11/11
Single -cell analysis
Cardiovascular
Heart diseases
Transcriptomics
Data analysis
Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain
期刊论文
OAI收割
FEBS OPEN BIO, 2022, 卷号: 12, 期号: 9, 页码: 1644-1656
作者:
Liu, Xin-Yuan
;
Chen, Yi-Li
;
Liu, Guo-Jian
;
Deng, Xiang-Nan
;
Cui, Yue
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/09/30
ADCC
affinity maturation
antibody engineering
anti-GD2 antibodies
engineered Fc domain
humanized
Rhodium(I) Carbene-Promoted Enantioselective C-H Functionalization of Simple Unprotected Indoles, Pyrroles and Heteroanalogues: New Mechanistic Insights
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 34, 页码: e202207008
作者:
Wang, Tian-Yi
;
Chen, Xiao-Xuan
;
Zhu, Dong-Xing
;
Chung, Lung Wa
;
Xu, Ming-Hua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21
Asymmetric Catalysis
C-H Functionalization
Carbene Insertion
Chiral Diene
Unprotected Indoles
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
He, Yi-fei
;
Liu, Yin
;
Yu, Jing-hua
;
Cheng, Huan
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
TPN171
[C-14]TPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Progress in the treatment of diabetic peripheral neuropathy
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 148, 页码: 10
作者:
Yang, Ke
;
Wang, Yue
;
Li, Yi-wei
;
Chen, Yi-gong
;
Xing, Na
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Diabetes Mellitus
Peripheral Nervous System Diseases
Chemical medicine
Traditional Chinese medicine
Acupuncture
Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702
作者:
Song, Zilan
;
Liu, Bo
;
Peng, Xia
;
Gu, Wangting
;
Sun, Yiming
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/06/15
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells
期刊论文
OAI收割
ACS applied bio materials, 2021, 卷号: 4, 期号: 9, 页码: 7016-7024
作者:
Zhao, Dan
;
Han, Hai-Hao
;
Zhu, Ling
;
Xu, Fang-Zhou
;
Ma, Xing-Yu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/15
aggregation-induced emission (AIE)
mitochondria
photodynamic therapy (PDT)
photosensitizer
theranostic probe
Noreudesmane sesquiterpenoids from Artemisia hedinii and their anti-inflammatory activities
期刊论文
OAI收割
FITOTERAPIA, 2021, 卷号: 153, 页码: 9
作者:
Wang, Xing
;
Tang, Chunping
;
Meng, Suoriya
;
Tang, Bixi
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
Artemisia hedinii
Sesquiterpenoid
Dinoreudesmane
Trinoreudesmane
Anti-inflammatory activity
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy