中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [42]
采集方式
OAI收割 [42]
内容类型
期刊论文 [42]
发表日期
2023 [42]
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专题:上海药物研究所
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发表日期:2023
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Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
Lin, Jia-Ling
;
Chen, Longxian
;
Wu, Wen-Kai
;
Guo, Xiao-Xiang
;
Yu, Cheng-Hui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Total synthesis of (±)-villosin C and (±)-teuvincenone B
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2023, 页码: 5
作者:
Zhou, Jin-Xin
;
Yan, Ming-Jie
;
Shi, Xiao-Yu
;
Wang, Yue-Qi
;
Shen, Hong-Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 17
作者:
Wang, Yu-Jun
;
Zan, Gui-Ying
;
Xu, Cenglin
;
Li, Xue-Ping
;
Shu, Xuelian
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/19
Amuc_1100 pretreatment alleviates acute pancreatitis in a mouse model through regulating gut microbiota and inhibiting inflammatory infiltration
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Li-juan
;
Jin, Yuan-ling
;
Pei, Wen-long
;
Li, Jia-cong
;
Zhang, Rui-lin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
acute pancreatitis
Amuc_1100
inflammation
gut microbiota
tryptophan metabolism
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
期刊论文
OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:
Chen, Yefei
;
Hong, Zexuan
;
Wang, Jingyi
;
Liu, Kunlin
;
Liu, Jing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 260, 页码: 14
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Chen, Yitong
;
Li, Huilin
;
Wang, Jin 'e
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Rice blast
Trehalose-6-phosphate synthase
Isopropanolamine compounds
Inhibitor
Fungicidal mechanism
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts